{"id":"W2418155678","doi":"10.1385/1-59259-079-9:177","title":"Gene Therapy Vectors Harboring AFP Regulatory Sequences: Preparation of an Adenoviral Vector","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Genetic enhancement; Vector (molecular biology); Gene; Viral vector; Cancer research; Biology; Hepatocellular carcinoma; Vectors in gene therapy; Regulatory sequence; Cytotoxic T cell; Gene expression; Computational biology; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006075899,0.0007069302,0.0004290675,0.0006017573,0.0003208609,0.0004440602,0.0003700093,0.0006187414,0.001545591],"category_scores_gemma":[0.000414697,0.0003901995,0.0003027707,0.000494067,0.0004199423,0.000465118,0.0003443215,0.001256214,0.001353124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003300574,"about_ca_system_score_gemma":0.0005447361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003295141,"about_ca_topic_score_gemma":0.0004122163,"domain_scores_codex":[0.999736,0.00005294176,0.00003137353,0.00004256798,0.00009913732,0.00003797458],"domain_scores_gemma":[0.9998889,0.00003080002,0.00002114939,0.00001654752,0.00001903918,0.0000236047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001539971,0.00009013944,0.00008438827,0.0002157009,0.000008173511,0.0001262713,0.00006691877,0.0003305108,0.9801357,0.002986998,0.0004096933,0.01539154],"study_design_scores_gemma":[0.00005780908,0.0003814648,0.0002372771,0.00003106887,0.00002619065,0.0004156609,0.00001647263,0.0007239613,0.9514488,0.0005066926,0.0461385,0.00001605932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2570955,0.01463982,0.6974419,0.001161871,0.001125518,0.005095396,0.003016738,0.001546144,0.01887701],"genre_scores_gemma":[0.3906215,0.01806163,0.5512401,0.0003991425,0.0002013858,0.002751857,0.005549558,0.0003474128,0.0308274],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001545591,"threshold_uncertainty_score":0.005170465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05716986963863872,"score_gpt":0.3319615098801754,"score_spread":0.2747916402415367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}