{"id":"W2419231850","doi":"10.1038/srep17686","title":"Epigenomic Reprogramming of Adult Cardiomyocyte-Derived Cardiac Progenitor Cells","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cedars-Sinai Medical Center; Division of Chemistry; Massachusetts General Hospital; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; National Institutes of Health; National Science Foundation","keywords":"Reprogramming; Epigenomics; Progenitor cell; Progenitor; Biology; Cell biology; Computational biology; Stem cell; Genetics; DNA methylation; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008329906,0.0001398645,0.000122512,0.0001698277,0.00006676528,0.0001424848,0.00009441948,0.00008064923,0.0004805342],"category_scores_gemma":[0.00009134615,0.00007710668,0.0001215168,0.0001158759,0.00007552274,0.00008525393,0.0001770195,0.0001833021,0.0001256477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007239635,"about_ca_system_score_gemma":0.0000927439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002531793,"about_ca_topic_score_gemma":0.0005561522,"domain_scores_codex":[0.9999425,0.000007268345,0.000004045173,0.00001946908,0.00001735268,0.000009249511],"domain_scores_gemma":[0.9999666,0.000006804065,0.000008411167,0.000005850878,0.000005643975,0.000006685597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001525129,0.000002605237,0.0004228753,0.0000112566,0.000002859304,0.00002509884,0.000009505517,0.00006061249,0.9973186,0.00006782996,0.000009798923,0.002053795],"study_design_scores_gemma":[0.000005472057,0.0001246592,0.03220244,0.000005926643,0.00003079869,0.0003861078,0.00004024736,0.001537376,0.9604443,0.0001245332,0.005093121,0.000005046006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777165,0.001501747,0.01745019,0.00004577026,0.00002408074,0.00003332015,0.0009821372,0.00007295404,0.002173228],"genre_scores_gemma":[0.9886574,0.001453169,0.006493977,0.00005432491,0.00001056992,0.00004300763,0.001254831,0.00002135887,0.002011356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004805342,"threshold_uncertainty_score":0.001607537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01786971453523468,"score_gpt":0.2742946182333746,"score_spread":0.2564249036981399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}