{"id":"W2419466400","doi":"10.1159/000458779","title":"Interactions of Divalent Cations and Nucleotides withSolubilized Cardiac Guanylate Cyclase","year":2017,"lang":"en","type":"article","venue":"Enzyme","topic":"Metalloenzymes and iron-sulfur proteins","field":"Energy","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"GUCY1B3; GUCY1A3; GTP'; Chemistry; Divalent; Solubilization; Enzyme; Nucleotide; Biochemistry; Guanylate cyclase; Inhibitory postsynaptic potential; Guanylate cyclase 2C; Catalysis; Biophysics; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001674335,0.0001391724,0.0002719507,0.00006071286,0.0003767631,0.00008126214,0.0002218031,0.00004605349,0.0006087233],"category_scores_gemma":[0.0002160824,0.0001241346,0.000117157,0.00003686762,0.0001678692,0.000285466,0.0001523478,0.0001199234,0.00006879228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002271985,"about_ca_system_score_gemma":0.00002522741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003034441,"about_ca_topic_score_gemma":0.0007216341,"domain_scores_codex":[0.9991068,0.00006356007,0.0002675711,0.000234694,0.0001389667,0.0001884016],"domain_scores_gemma":[0.9987039,0.0000641497,0.0002262012,0.0008370662,0.00006336602,0.0001053149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002870281,0.0008643839,0.02018066,0.0003538742,0.001177608,0.00003287137,0.004711438,0.0008574376,0.3780107,0.4849145,0.01785064,0.09075894],"study_design_scores_gemma":[0.002495944,0.0002654573,0.2048658,0.0002527169,0.0003662635,0.00001866109,0.0005786164,0.002291326,0.189635,0.0100929,0.588252,0.0008852837],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9472622,0.000737503,0.0002134513,0.001353112,0.0007051845,0.0002810838,0.00005173083,0.00006414136,0.04933162],"genre_scores_gemma":[0.9923189,0.0001914912,0.001234128,0.00003500556,0.0001376997,0.0000384203,0.00001014858,0.00002431416,0.006009889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5704014,"threshold_uncertainty_score":0.6665093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02393561246288005,"score_gpt":0.2784903603066032,"score_spread":0.2545547478437231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}