{"id":"W2421079281","doi":"10.1158/2326-6074.tumimm14-a49","title":"Abstract A49: Systemic oncolytic reovirus for the treatment of primary and secondary brain tumors","year":2015,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"","keywords":"Oncolytic virus; Medicine; Virotherapy; Glioma; Immunotherapy; Radiation therapy; Cancer research; Systemic administration; Immune system; Immunology; In vivo; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001458969,0.0001554092,0.0002778795,0.0001203733,0.0001752028,0.00002306948,0.0004011695,0.0001856338,0.00003355596],"category_scores_gemma":[0.0001693094,0.0001114864,0.00008274169,0.0001627443,0.0008140521,0.000005431116,0.0001237436,0.000226899,0.000008943231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002964753,"about_ca_system_score_gemma":0.001847272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003182181,"about_ca_topic_score_gemma":0.0003096942,"domain_scores_codex":[0.9982791,0.0002820027,0.0002606919,0.0003929071,0.0002542685,0.0005310547],"domain_scores_gemma":[0.9983716,0.0003924911,0.00007466794,0.000635415,0.0004210368,0.0001048053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007961011,0.0001369067,0.0005650275,0.00009860994,0.000420571,0.000006904352,0.00039137,0.00003090558,0.8717325,0.00002584713,0.003776239,0.1148542],"study_design_scores_gemma":[0.007547454,0.02366493,0.006816248,0.00009313214,0.00003151877,0.00008635219,0.001587397,0.00006581079,0.8367049,0.000220831,0.122862,0.0003194172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8847792,0.112273,0.00001482517,0.00103858,0.0001205147,0.001051989,0.00008527719,0.000007242296,0.0006294566],"genre_scores_gemma":[0.9859676,0.01049244,0.0000251439,0.0001086237,0.0002393995,0.0009229399,0.00005054554,0.00003866349,0.002154611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1190858,"threshold_uncertainty_score":0.4546283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08491880032555363,"score_gpt":0.3954175406100843,"score_spread":0.3104987402845306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}