{"id":"W2421079281","doi":"10.1158/2326-6074.tumimm14-a49","title":"Abstract A49: Systemic oncolytic reovirus for the treatment of primary and secondary brain tumors","year":2015,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"","keywords":"Oncolytic virus; Medicine; Virotherapy; Glioma; Immunotherapy; Radiation therapy; Cancer research; Systemic administration; Immune system; Immunology; In vivo; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001900069,0.000395877,0.0005292463,0.0002463904,0.0001563029,0.0003212494,0.0002390713,0.000345154,0.003497236],"category_scores_gemma":[0.0001106795,0.00008606973,0.0003814786,0.0001452922,0.0002742747,0.0001898993,0.0001890325,0.0009436992,0.0006135318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002489082,"about_ca_system_score_gemma":0.0004073272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007607598,"about_ca_topic_score_gemma":0.001042095,"domain_scores_codex":[0.9999197,0.00001344676,0.0000045934,0.00002179105,0.00001612363,0.00002441756],"domain_scores_gemma":[0.9999156,0.00001762992,0.0000115602,0.00001193548,0.000007517855,0.00003573587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006124793,0.003525284,0.001533803,0.0002632077,0.00008877455,0.0003996404,0.00006096807,0.0009961805,0.9244115,0.0005302872,0.002154018,0.05991145],"study_design_scores_gemma":[0.005934323,0.1252087,0.02157936,0.00006697521,0.0003108891,0.00363651,0.00007210068,0.005617633,0.8196622,0.0003697751,0.01750506,0.00003643373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985879,0.002758296,0.005176875,0.000242132,0.0001552177,0.0005206433,0.0007653946,0.0001923152,0.004310148],"genre_scores_gemma":[0.990463,0.001431036,0.00326325,0.0001021771,0.00006353881,0.0003178531,0.001075533,0.00003921548,0.003244403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003497236,"threshold_uncertainty_score":0.01169944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08491880032555363,"score_gpt":0.3954175406100843,"score_spread":0.3104987402845306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}