{"id":"W2421289519","doi":"10.4238/gmr.15028579","title":"Altered expression of CG5961, a putative Drosophila melanogaster homologue of FBXO9, provides a new model of Parkinson disease","year":2016,"lang":"en","type":"article","venue":"Genetics and Molecular Research","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland","keywords":"Drosophila melanogaster; Biology; Gene; Genetics; Melanogaster; RNA interference; Neurodegeneration; Gene expression; Dopaminergic; Cell biology; Neuroscience; Disease; RNA; Dopamine; Pathology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004091744,0.0004752301,0.0001929554,0.0002467141,0.0001708894,0.000170741,0.0002590673,0.0004135991,0.001032411],"category_scores_gemma":[0.00003274243,0.0001036685,0.0002287633,0.0001132456,0.0002208006,0.0001464659,0.0001816973,0.0003936914,0.000307288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003637634,"about_ca_system_score_gemma":0.0001105947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008389805,"about_ca_topic_score_gemma":0.0009503936,"domain_scores_codex":[0.999949,0.000004960547,0.000005876341,0.00001795749,0.00001428576,0.000007926144],"domain_scores_gemma":[0.9999721,0.000003913563,0.00000961808,0.000003624109,0.000002152337,0.000008591353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005423829,0.00001423983,0.0001527241,0.00002415739,0.000003353858,0.000186204,0.000004610091,0.00006091467,0.9983316,0.000232208,0.0000406068,0.0008951277],"study_design_scores_gemma":[0.0000418218,0.0003938645,0.008519677,0.00001764286,0.00003148208,0.001993821,0.00003375901,0.00254767,0.9749566,0.0003815733,0.01107128,0.00001067435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855837,0.002257464,0.006301064,0.0001825506,0.00005020396,0.00006627163,0.001420476,0.0001557435,0.003982712],"genre_scores_gemma":[0.9877582,0.001163227,0.004565834,0.0000637691,0.00000784076,0.00004504088,0.001296628,0.00002070763,0.005078662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001032411,"threshold_uncertainty_score":0.003453791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05609687336722361,"score_gpt":0.3245394797299355,"score_spread":0.2684426063627118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}