{"id":"W2421436919","doi":"","title":"Use of predictive biomarkers in phase 2 trials.","year":2015,"lang":"en","type":"other","venue":"PubMed","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; MEDLINE; Internal medicine; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01219629,0.0007096741,0.002505194,0.002580941,0.0002134111,0.002593472,0.00107481,0.001181313,0.02798394],"category_scores_gemma":[0.06893369,0.0003048138,0.002109191,0.004424742,0.0002435547,0.001425248,0.0007246686,0.00115904,0.003412527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007772426,"about_ca_system_score_gemma":0.002670306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001149235,"about_ca_topic_score_gemma":0.00254684,"domain_scores_codex":[0.9920082,0.005129773,0.001424624,0.0004606546,0.0008556028,0.0001210867],"domain_scores_gemma":[0.9553384,0.03368494,0.006393358,0.001280092,0.002698855,0.0006042933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01365512,0.0002049237,0.005337279,0.1337976,0.01244811,0.0001117529,0.00006923168,0.0009944256,0.0009139728,0.006116437,0.1964083,0.6299429],"study_design_scores_gemma":[0.03784604,0.004286665,0.04555606,0.1946408,0.05865345,0.0007263225,0.0001595763,0.004240422,0.00398161,0.02414146,0.6255491,0.0002185085],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.007213656,0.8576496,0.007444899,0.01191208,0.002916386,0.003566711,0.06708759,0.0005996972,0.04160935],"genre_scores_gemma":[0.213367,0.6767967,0.02591277,0.009990966,0.004157469,0.009661916,0.04880454,0.0003519984,0.01095663],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.02798394,"threshold_uncertainty_score":0.09361559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6606047723079976,"score_gpt":0.4550872139783588,"score_spread":0.2055175583296388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}