{"id":"W2422331992","doi":"10.1007/978-1-61779-504-6_13","title":"Blue Native Polyacrylamide Gel Electrophoresis: A Powerful Diagnostic Tool for the Detection of Assembly Defects in the Enzyme Complexes of Oxidative Phosphorylation","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Oxidative phosphorylation; Enzyme; Polyacrylamide gel electrophoresis; Biochemistry; Biology; Mitochondrial disease; Mitochondrion; Gel electrophoresis; Molecular biology; Mitochondrial DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001258434,0.00135082,0.0005066596,0.003028597,0.0005570257,0.0007370453,0.0008920872,0.001196209,0.001898417],"category_scores_gemma":[0.0008017424,0.0004628281,0.0002525436,0.001137166,0.0009359113,0.001276146,0.0008454738,0.001571507,0.002000181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002101895,"about_ca_system_score_gemma":0.0003671826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003014104,"about_ca_topic_score_gemma":0.0005345792,"domain_scores_codex":[0.9992663,0.0002260578,0.00005100259,0.0001657062,0.0002298679,0.0000610743],"domain_scores_gemma":[0.9992618,0.0002362771,0.0001735994,0.00008566657,0.000104509,0.0001382084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006394695,0.00003140259,0.0004964098,0.0002002985,0.000017727,0.0001541412,0.0000720408,0.00002553729,0.9885541,0.0004355058,0.0006889504,0.009259914],"study_design_scores_gemma":[0.00003758122,0.0004659297,0.01179034,0.0001187032,0.00009301404,0.006425361,0.0001744669,0.001695426,0.9331651,0.001824627,0.04415627,0.00005316547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2101221,0.1006385,0.6528199,0.003593123,0.001424437,0.0003040877,0.002283234,0.007829525,0.02098512],"genre_scores_gemma":[0.3678477,0.07254087,0.5298504,0.001412753,0.0006232327,0.0004959068,0.004067628,0.0006903631,0.02247122],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003028597,"threshold_uncertainty_score":0.006655335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02281157062943791,"score_gpt":0.3247289376103987,"score_spread":0.3019173669809608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}