{"id":"W2423873916","doi":"10.1089/aid.2015.0381","title":"Rectal 1% Tenofovir Gel Use Associates with Altered Epidermal Protein Expression","year":2016,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Public Health Agency of Canada; National Institutes of Health; National Institute of Mental Health; Public Health Agency; National Institute of Allergy and Infectious Diseases; University of Pittsburgh","keywords":"Tenofovir; Chemistry; Protein expression; Reverse-transcriptase inhibitor; Molecular biology; Virology; Biology; Virus; Human immunodeficiency virus (HIV); Biochemistry; Viral disease; Sida; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0007888193,0.0002317705,0.0003176325,0.0003360418,0.00096905,0.0001374779,0.0002651013,0.0002004933,0.001142637],"category_scores_gemma":[0.0005846194,0.0001229832,0.00005792689,0.0001773369,0.001143926,0.0004705446,0.0002798097,0.0004896675,0.0009429657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001345416,"about_ca_system_score_gemma":0.0001179771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007706106,"about_ca_topic_score_gemma":0.0002573486,"domain_scores_codex":[0.9969115,0.000803092,0.0002412626,0.0005663019,0.0002484075,0.001229483],"domain_scores_gemma":[0.9983107,0.0007596962,0.0000683598,0.0004194287,0.0002700672,0.0001717672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007550176,0.0002607014,0.2925862,0.00001778774,0.0001763831,0.00005731887,0.0001174353,1.059301e-8,0.6948612,0.0007938818,0.005846604,0.004527533],"study_design_scores_gemma":[0.005357871,0.009562463,0.3511095,0.0003999454,0.00001609557,0.00004373835,0.0001842179,2.244617e-8,0.6018842,0.0009203356,0.03017632,0.0003452699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970817,0.0007091885,0.00002187636,0.0002442695,0.00002923087,0.0006509627,0.0002054794,0.00008677069,0.0009704977],"genre_scores_gemma":[0.9723051,0.000128083,0.0001639609,0.00002333344,0.00006669991,0.0002093664,0.00006761217,0.00003280024,0.02700305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09297696,"threshold_uncertainty_score":0.9998349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07553864998445196,"score_gpt":0.3367026101590168,"score_spread":0.2611639601745648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}