{"id":"W2423873916","doi":"10.1089/aid.2015.0381","title":"Rectal 1% Tenofovir Gel Use Associates with Altered Epidermal Protein Expression","year":2016,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Public Health Agency of Canada; National Institutes of Health; National Institute of Mental Health; Public Health Agency; National Institute of Allergy and Infectious Diseases; University of Pittsburgh","keywords":"Tenofovir; Chemistry; Protein expression; Reverse-transcriptase inhibitor; Molecular biology; Virology; Biology; Virus; Human immunodeficiency virus (HIV); Biochemistry; Viral disease; Sida; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006728231,0.0002720955,0.0004966718,0.0002385854,0.0001291395,0.0004263448,0.00009157517,0.000314097,0.001197404],"category_scores_gemma":[0.000842625,0.0001513531,0.000344001,0.0002044751,0.0002487497,0.000224499,0.0001186465,0.0004977614,0.0001230909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001785801,"about_ca_system_score_gemma":0.0001323172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003246419,"about_ca_topic_score_gemma":0.0005056484,"domain_scores_codex":[0.9995195,0.0001904154,0.00002324363,0.0001033843,0.0001091487,0.00005434732],"domain_scores_gemma":[0.9994255,0.0001450044,0.0002981065,0.0000462006,0.0000355279,0.00004970314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03863341,0.001224146,0.05605054,0.0006524506,0.0002781239,0.0005564404,0.0001910945,0.0003052993,0.8305588,0.00009144723,0.0004457966,0.07101238],"study_design_scores_gemma":[0.0005450278,0.0424087,0.7048765,0.00009065044,0.0005504426,0.004483938,0.0003887227,0.002353904,0.2410806,0.0001995249,0.0029755,0.00004658717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981054,0.001133371,0.0003157524,0.000040868,0.00001041956,0.00001793681,0.00006193736,0.00001249908,0.0003017422],"genre_scores_gemma":[0.9988574,0.0003388917,0.0004271187,0.00003583144,0.000006230569,0.00001210261,0.00004520974,0.00000349282,0.0002737296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001197404,"threshold_uncertainty_score":0.004005671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07553864998445196,"score_gpt":0.3367026101590168,"score_spread":0.2611639601745648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}