{"id":"W2428351003","doi":"10.1007/978-1-61779-139-0_15","title":"CELLISA: Reporter Cell-Based Immunization and Screening of Hybridomas Specific for Cell Surface Antigens","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto","funders":"","keywords":"Antigen; Monoclonal antibody; Epitope; Immunogenicity; Biology; Chimeric antigen receptor; Molecular biology; Antibody; Immunization; Cell; T cell; Immune system; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009880696,0.00129866,0.001018632,0.0008772346,0.0002620929,0.0008604394,0.001111365,0.0009788194,0.001413801],"category_scores_gemma":[0.0003909507,0.0004039615,0.0005856206,0.0005933899,0.0004173072,0.0003718783,0.0007308606,0.001531723,0.001310085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003958802,"about_ca_system_score_gemma":0.0002766729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003156014,"about_ca_topic_score_gemma":0.0004286847,"domain_scores_codex":[0.9991689,0.0001916507,0.0000560732,0.000149557,0.0002823389,0.0001515236],"domain_scores_gemma":[0.9997311,0.00006320082,0.00006304779,0.00005251127,0.00004942471,0.00004067846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005305637,0.00004571595,0.0001354497,0.00005981866,0.00001169787,0.00003529658,0.00001732579,0.0001190778,0.9962646,0.0002407046,0.0001663627,0.002850906],"study_design_scores_gemma":[0.00001423875,0.0001788004,0.0004444967,0.000004268745,0.00001577382,0.000202528,0.000008663179,0.001301868,0.9935271,0.00006789591,0.004227062,0.000007463591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4749698,0.003444572,0.5059261,0.0004673197,0.0001873222,0.001549991,0.003169835,0.003762653,0.006522487],"genre_scores_gemma":[0.7537194,0.004233143,0.2182665,0.0004211718,0.0001016944,0.001763792,0.007897363,0.0004060924,0.01319075],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001413801,"threshold_uncertainty_score":0.00522548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0390042957580006,"score_gpt":0.3212772831267964,"score_spread":0.2822729873687958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}