{"id":"W2430387656","doi":"10.1021/acs.molpharmaceut.5b00261","title":"A <sup>1</sup>H NMR Study of Host/Guest Supramolecular Complexes of a Curcumin Analogue with β-Cyclodextrin and a β-Cyclodextrin-Conjugated Gemini Surfactant","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmaceutics","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Light Source (Canada); University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemistry; Supramolecular chemistry; Cyclodextrin; Amphiphile; Curcumin; Pulmonary surfactant; Conjugated system; Proton NMR; Aqueous solution; Nuclear magnetic resonance spectroscopy; Two-dimensional nuclear magnetic resonance spectroscopy; Molecule; Supramolecular assembly; Stereochemistry; Micelle; Solubility; Crystallography; Organic chemistry; Copolymer; Polymer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001908221,0.0007281599,0.001332476,0.0004133678,0.0001773212,0.00004975235,0.0006628472,0.0004441748,0.00007396189],"category_scores_gemma":[0.0001710216,0.0006894839,0.0001843805,0.0009928788,0.0007887681,0.0002104133,0.0003917244,0.001069852,0.00002314654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001054274,"about_ca_system_score_gemma":0.0003339734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006429783,"about_ca_topic_score_gemma":0.00007740253,"domain_scores_codex":[0.9941804,0.001842221,0.001353476,0.0008685088,0.0008772405,0.0008781699],"domain_scores_gemma":[0.9965611,0.0004177697,0.0006774651,0.0007521107,0.0007507259,0.0008408414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01155732,0.01533455,0.2703741,0.001743321,0.007170916,0.004344725,0.03972756,0.06793102,0.5744792,0.001586776,0.003196613,0.002553832],"study_design_scores_gemma":[0.04978979,0.007921051,0.002736088,0.0003468846,0.004369709,0.0009724752,0.02118829,0.1218616,0.6997289,0.0001967999,0.08798541,0.002902972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918005,0.003045933,0.0009901988,0.0001312353,0.0003438066,0.002068184,0.0003106857,0.0001257032,0.001183751],"genre_scores_gemma":[0.9985501,0.0001654483,0.0002980673,0.0005009849,0.00008877509,0.00007343738,0.00008578321,0.00009763563,0.0001398052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2676381,"threshold_uncertainty_score":0.9995556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1051167010787643,"score_gpt":0.3861229715025465,"score_spread":0.2810062704237822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}