{"id":"W2431521472","doi":"10.1111/iju.13137","title":"Androgen receptor targeted therapies in castration‐resistant prostate cancer: Bench to clinic","year":2016,"lang":"en","type":"review","venue":"International Journal of Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Enzalutamide; Prostate cancer; Androgen receptor; Medicine; Cabazitaxel; Androgen deprivation therapy; Androgen; Abiraterone acetate; Cancer research; Androgen Receptor Antagonists; Internal medicine; Cancer; Oncology; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004760608,0.0002323111,0.001060119,0.0007992087,0.00002159157,0.000025262,0.0003574518,0.0001981098,0.001415593],"category_scores_gemma":[0.0001456656,0.0001367294,0.0003228648,0.0001874209,0.00007949774,0.00008615987,0.00006005606,0.0004708759,0.0001115893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005856147,"about_ca_system_score_gemma":0.001664634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002766733,"about_ca_topic_score_gemma":0.00004225972,"domain_scores_codex":[0.9977584,0.0001917935,0.001038383,0.0002372297,0.0005019241,0.0002722444],"domain_scores_gemma":[0.9982367,0.0002171236,0.0005983549,0.0001316165,0.0006490867,0.0001671128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002411248,0.0001992249,0.0008765318,0.0004268755,0.001836753,0.001019755,0.000291153,0.000001153914,0.0002079626,0.00002828321,0.004398705,0.9883024],"study_design_scores_gemma":[0.001892401,0.001123589,0.0002473243,0.003474824,0.0001758971,0.0003867994,0.00001719942,3.158114e-7,0.00002453416,0.0001027646,0.9924359,0.0001184584],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001441876,0.9878041,0.000005052676,0.008389045,0.001343766,0.0005918514,0.0002310952,0.000006391184,0.0001868806],"genre_scores_gemma":[0.001053501,0.9958426,0.0001446893,0.000274945,0.0007757354,0.0000807137,0.00006397752,0.00003203956,0.001731782],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9881839,"threshold_uncertainty_score":0.9994972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05431369724814229,"score_gpt":0.4238036131582497,"score_spread":0.3694899159101074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}