{"id":"W2432175231","doi":"10.1159/000468901","title":"Mammalian Neural and Endocrine Pro-Protein andPro-Hormone Convertases Belonging to the Subtilisin Familyof Serine Proteinases","year":2017,"lang":"en","type":"review","venue":"Enzyme","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Furin; Proprotein Convertases; Prohormone convertase; Kexin; Biochemistry; Biology; Subtilisin; Enzyme; Protein precursor; Serine; Serine protease; Cell biology; Hormone; Prohormone; Protease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000393218,0.000982729,0.0009299053,0.002279174,0.0002876623,0.0009496124,0.0006190434,0.0005591186,0.003142643],"category_scores_gemma":[0.0004053399,0.0002221955,0.000309469,0.002774752,0.0004610605,0.001134627,0.0005809612,0.001355999,0.002575574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005621974,"about_ca_system_score_gemma":0.001147716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007445744,"about_ca_topic_score_gemma":0.001358331,"domain_scores_codex":[0.999843,0.00001636425,0.00002422792,0.00002608485,0.00007220772,0.00001804451],"domain_scores_gemma":[0.9998522,0.00003650708,0.00003248454,0.00000633325,0.00004712883,0.00002533945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006036096,0.00004046886,0.0002038792,0.009631297,0.00005573465,0.0001921387,0.00004829872,0.0002036202,0.003708546,0.003063241,0.01552594,0.9672665],"study_design_scores_gemma":[0.000007563741,0.00003626135,0.000714891,0.0009217801,0.00004253994,0.000935004,0.00003558343,0.0000337962,0.0007307234,0.00108747,0.9954444,0.000009957475],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000209178,0.9973083,0.00026175,0.0001707939,0.000151303,0.000006837654,0.00003576049,0.00001322007,0.00184283],"genre_scores_gemma":[0.00089646,0.9972307,0.0003159454,0.00009071959,0.00008191869,0.00000686063,0.0000686206,0.000001809542,0.00130696],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003142643,"threshold_uncertainty_score":0.01051325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0417152262584698,"score_gpt":0.3025710895637531,"score_spread":0.2608558633052833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}