{"id":"W2433290391","doi":"","title":"Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.","year":2001,"lang":"en","type":"article","venue":"PubMed","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"","keywords":"Nimesulide; Medicine; Cyclooxygenase; BETA (programming language); Gene expression; Naproxen; Prostaglandin E2; Pharmacology; Endocrinology; Molecular biology; Internal medicine; Gene; Enzyme; Biology; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001668463,0.000259134,0.0003215662,0.000211015,0.0001598576,0.0002746774,0.00009093393,0.0001944844,0.0008966227],"category_scores_gemma":[0.0001464307,0.00011271,0.0002413752,0.0001823922,0.0001859474,0.0001369273,0.0001111709,0.0002963103,0.0002763863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002056871,"about_ca_system_score_gemma":0.0001709412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001066828,"about_ca_topic_score_gemma":0.002040113,"domain_scores_codex":[0.9998108,0.00004142224,0.00002064842,0.00003027789,0.00005742623,0.00003945466],"domain_scores_gemma":[0.9999081,0.00003470928,0.00001550881,0.00001263945,0.00001448944,0.0000145072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001949469,0.00002402133,0.0001984871,0.00003598869,0.00000276866,0.00007298612,0.0000270205,0.00002517868,0.9983484,0.00003570702,0.00002219022,0.001012441],"study_design_scores_gemma":[0.00004542716,0.0004334585,0.009202845,0.000006505357,0.0000210339,0.0002438949,0.00008266621,0.0006048635,0.9869518,0.00004629792,0.002353945,0.00000718974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882854,0.006355558,0.001934132,0.0001193773,0.00008970721,0.00005380587,0.0007714027,0.00003563837,0.002355005],"genre_scores_gemma":[0.9911104,0.002641227,0.003071614,0.00005981086,0.00003053599,0.0001074966,0.000574041,0.000006703,0.002398225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001066828,"threshold_uncertainty_score":0.002999544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01487792239523705,"score_gpt":0.2336803431543346,"score_spread":0.2188024207590975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}