{"id":"W2434541788","doi":"10.1021/acs.jpcb.5b07375","title":"Conformational Changes and Association of Membrane-Interacting Peptides in Myelin Membrane Models: A Case of the C-Terminal Peptide of Proteolipid Protein and the Antimicrobial Peptide Melittin","year":2015,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Melittin; Peptide; Chemistry; Myelin proteolipid protein; Membrane; Proteolipid protein 1; Biophysics; Circular dichroism; Vesicle; Transmembrane domain; Transmembrane protein; Random coil; Myelin basic protein; Myelin; Biochemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009236704,0.0001931767,0.0001036126,0.00008700693,0.0001060239,0.0001495032,0.000143852,0.0002096501,0.000248214],"category_scores_gemma":[0.0001650393,0.00008240297,0.0001192319,0.00008485295,0.0001481585,0.0002266955,0.0001345601,0.0001935211,0.00006432881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001388469,"about_ca_system_score_gemma":0.00007537597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003465604,"about_ca_topic_score_gemma":0.0002575891,"domain_scores_codex":[0.999951,0.00001182951,0.000002308326,0.00001232115,0.00001162604,0.00001085802],"domain_scores_gemma":[0.9999615,0.000009278319,0.00001266309,0.000004069223,0.000006423038,0.000006083182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008549898,0.00001338262,0.0003896465,0.00001840728,0.000005663511,0.00006458432,0.00002867831,0.0006612986,0.9981176,0.0001622001,0.000007155267,0.0004458233],"study_design_scores_gemma":[0.00001799074,0.0003161012,0.003666979,0.000008869803,0.00002249021,0.0003442916,0.0001029444,0.02127911,0.9731607,0.0002296129,0.0008380663,0.00001278734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990597,0.00009037698,0.0007254459,0.000007627321,0.00000101997,0.000002106998,0.00001352758,0.000003526943,0.00009659393],"genre_scores_gemma":[0.9989286,0.0001127328,0.0007342738,0.000006435285,6.188064e-7,0.000006112791,0.00004970804,0.000002589074,0.0001588538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003465604,"threshold_uncertainty_score":0.001007438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01164979945817964,"score_gpt":0.2463400984401863,"score_spread":0.2346902989820067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}