{"id":"W2434582744","doi":"10.1182/blood.v122.21.1638.1638","title":"TP53 Mutation or Deletion and Efficacy with Single-Agent Lenalidomide in Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) (CC-5013-CLL-009 Study)","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Lenalidomide; Medicine; Internal medicine; Neutropenia; Bendamustine; Chronic lymphocytic leukemia; Oncology; Gastroenterology; Refractory (planetary science); Febrile neutropenia; Chemotherapy; Leukemia; Multiple myeloma; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002202843,0.0008480129,0.001212245,0.0003218208,0.0002872419,0.0007041349,0.0008055115,0.001012481,0.0026141],"category_scores_gemma":[0.0007573254,0.0003967359,0.0008089484,0.0002420922,0.0007345232,0.0004526788,0.0003145744,0.001272782,0.0004227406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007494925,"about_ca_system_score_gemma":0.0009828785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000715105,"about_ca_topic_score_gemma":0.001533525,"domain_scores_codex":[0.9991259,0.000528411,0.00004498042,0.000126197,0.00007427989,0.0001001637],"domain_scores_gemma":[0.9992647,0.0001355534,0.0001688923,0.00007600713,0.00004078488,0.0003141569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8657977,0.0244455,0.03683275,0.0003434833,0.001087197,0.0001814427,0.00008203642,0.001012536,0.0244813,0.0001378293,0.002362471,0.04323577],"study_design_scores_gemma":[0.5671976,0.3463275,0.07707046,0.00006374698,0.0009261072,0.0003853424,0.00004169099,0.001244065,0.004040956,0.0001630199,0.002496056,0.0000435048],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967645,0.001010217,0.0001196792,0.0001315812,0.00003330385,0.000566041,0.0006349214,0.00002613511,0.0007135047],"genre_scores_gemma":[0.9961708,0.0003606816,0.0004474036,0.0002708735,0.0001113926,0.0005632055,0.001198608,0.00000761685,0.0008693836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0026141,"threshold_uncertainty_score":0.01164985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02886515541554497,"score_gpt":0.2854078378169268,"score_spread":0.2565426824013818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}