{"id":"W2435850291","doi":"10.1016/s2468-1253(16)30001-2","title":"Ombitasvir, paritaprevir, and ritonavir plus ribavirin in adults with hepatitis C virus genotype 4 infection and cirrhosis (AGATE-I): a multicentre, phase 3, randomised open-label trial","year":2016,"lang":"en","type":"article","venue":"˜The œLancet. Gastroenterology & hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Liver Centre; University of Toronto","funders":"AbbVie","keywords":"Ribavirin; Ritonavir; Medicine; Ombitasvir; Paritaprevir; Cirrhosis; Virology; Open label; Internal medicine; Hepatitis C virus; Hepatitis C; Gastroenterology; Human immunodeficiency virus (HIV); Randomized controlled trial; Virus; Viral load; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001118381,0.0004868106,0.001793525,0.0003317379,0.0002153172,0.00006494295,0.0003890831,0.0003567053,0.0001273378],"category_scores_gemma":[0.0003513746,0.0003137855,0.00007048544,0.0002534874,0.001080519,0.0002964884,0.000480914,0.0007515521,0.00004848555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002580367,"about_ca_system_score_gemma":0.0001952396,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.008874305,"about_ca_topic_score_gemma":0.08219635,"domain_scores_codex":[0.9949698,0.001499477,0.0008810857,0.001031935,0.0003185965,0.001299069],"domain_scores_gemma":[0.9977582,0.000627527,0.0003108144,0.0007604845,0.0001658898,0.0003770511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.353527,0.0008035064,0.6200082,0.00008580962,0.0002319919,0.0003774944,0.0002160321,3.651355e-7,0.001331937,0.00002455625,0.0005679372,0.02282524],"study_design_scores_gemma":[0.8308691,0.01184806,0.1503595,0.0003791401,0.0002741351,0.0006178352,0.00001865428,0.001828946,0.0002189052,0.0001306437,0.00316447,0.0002906395],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898409,0.0004588017,0.0005456206,0.004072488,0.0002835438,0.004364554,0.0001216181,0.00007693651,0.000235558],"genre_scores_gemma":[0.9874856,0.008471417,0.0004899137,0.001995706,0.0002589226,0.001107028,0.00004955831,0.0000665698,0.00007526378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4773421,"threshold_uncertainty_score":0.9999314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04196157814196336,"score_gpt":0.3391781416447672,"score_spread":0.2972165635028039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}