{"id":"W2436307928","doi":"10.1016/b978-0-12-404634-4.00013-9","title":"De Novo Synthesis of High-Value Plant Sesquiterpenoids in Yeast","year":2012,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Terpenoid; Biochemistry; Sesquiterpene; Terpene; Biology; Metabolic engineering; Thioredoxin; Yeast; Enzyme; Chemistry; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01031929,0.000677797,0.001457636,0.0007348051,0.0000635168,0.0000129047,0.0009831516,0.001924134,0.0001644633],"category_scores_gemma":[0.005885345,0.0006768701,0.0002415495,0.0006662387,0.0006749996,0.00001954295,0.0004545626,0.000946896,0.000012446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002044988,"about_ca_system_score_gemma":0.0001961633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004106462,"about_ca_topic_score_gemma":0.0003810928,"domain_scores_codex":[0.9871708,0.008496707,0.00135568,0.001141219,0.0001994145,0.001636148],"domain_scores_gemma":[0.9951968,0.003005981,0.0004335085,0.001068265,0.00005582556,0.0002396861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001067812,0.001033526,0.03451268,0.0001160388,0.00009994522,0.0001611638,0.000241777,0.0002658735,0.9397889,0.002388991,0.0001439985,0.02017927],"study_design_scores_gemma":[0.001061625,0.000423883,0.1102123,0.0001309238,0.00005452845,0.0009278182,0.0001724589,0.00005252814,0.8813179,0.001715146,0.003276123,0.0006547854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822811,0.001235535,0.01215355,0.0002124122,0.0008864359,0.0003819249,0.0002062804,0.00003067881,0.002612083],"genre_scores_gemma":[0.5757039,0.0001824672,0.423046,0.0004740789,0.000214353,0.0001393446,0.00005967136,0.0000501775,0.000130058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4108924,"threshold_uncertainty_score":0.9995682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0278582850090767,"score_gpt":0.3597968835905396,"score_spread":0.3319385985814629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}