{"id":"W2437716483","doi":"10.1038/srep27204","title":"Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"RIKEN; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Nucleus accumbens; Methamphetamine; Knockout mouse; RNA splicing; Alternative splicing; Dopamine; Gene; Gene expression; Biology; Gene knockout; RNA; Neuroscience; Genetics; Pharmacology; Gene isoform","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001506687,0.0002216978,0.0001892651,0.0001170318,0.0003326435,0.0001101041,0.000327732,0.000129501,0.0001050139],"category_scores_gemma":[0.0005997051,0.0001261693,0.000109384,0.000505165,0.0003081339,0.00001307846,0.000231058,0.0001241108,0.00008021711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000760402,"about_ca_system_score_gemma":0.0004043791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004273835,"about_ca_topic_score_gemma":0.0003123944,"domain_scores_codex":[0.9971401,0.0002115049,0.0003019916,0.001183562,0.000637309,0.0005255511],"domain_scores_gemma":[0.9974684,0.00005530487,0.0001632861,0.001641863,0.000445503,0.0002256444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004186836,0.00005505636,0.00002321093,0.000007088474,0.00005176662,0.00008556294,0.00005163139,0.0002642548,0.9825706,0.00001356949,0.006921315,0.009537227],"study_design_scores_gemma":[0.0002914898,0.0001823819,0.0002363015,0.00006535813,0.00001381782,0.0002604958,0.00002644893,0.000007694053,0.7517214,0.0000788347,0.2469331,0.0001827035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9015021,0.0004449686,0.09075671,0.003014005,0.002523686,0.000806112,0.00001886629,0.00002608687,0.0009074175],"genre_scores_gemma":[0.972038,0.00002703882,0.001306401,0.0001955118,0.0001791668,0.0001221469,0.00003994154,0.00004215227,0.02604961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2400117,"threshold_uncertainty_score":0.5145034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361253919852068,"score_gpt":0.2892303594933875,"score_spread":0.2756178202948668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}