{"id":"W2440656793","doi":"10.3892/ijmm.2016.2640","title":"NF-κB signaling maintains the survival of cadmium-exposed human renal glomerular endothelial cells","year":2016,"lang":"en","type":"article","venue":"International Journal of Molecular Medicine","topic":"Heavy Metal Exposure and Toxicity","field":"Environmental Science","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trent University","funders":"Science and Technology Development Plan of Shandong Province; National Natural Science Foundation of China","keywords":"Pyrrolidine dithiocarbamate; NF-κB; Apoptosis; Kidney; Cancer research; Signal transduction; Biology; Oncogene; Cell biology; Cadmium chloride; Cell cycle; Kinase; Internal medicine; Chemistry; Endocrinology; Pharmacology; Cadmium; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001153535,0.0001387254,0.0002560567,0.0001299659,0.0001775549,0.0002699376,0.0001220049,0.0001733318,0.001109746],"category_scores_gemma":[0.0000916164,0.00007438189,0.0002112016,0.0001236683,0.0001233852,0.000160615,0.0001554032,0.0004107262,0.0002920269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001564032,"about_ca_system_score_gemma":0.0002422098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007286675,"about_ca_topic_score_gemma":0.0009351305,"domain_scores_codex":[0.9998864,0.00001476396,0.00001061929,0.00002906684,0.00003171203,0.00002747789],"domain_scores_gemma":[0.9999515,0.000004641174,0.00001064145,0.000007141441,0.00001487097,0.0000111873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002631349,0.00005440908,0.0006850857,0.00007470676,0.000008258735,0.00007621342,0.00004323683,0.00005869837,0.9964024,0.0000533903,0.00006452586,0.002215876],"study_design_scores_gemma":[0.00003151013,0.0003843993,0.0147486,0.00001679502,0.00002404837,0.0003264556,0.0001383717,0.0007013422,0.9785194,0.00007855127,0.005021963,0.000008710266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902147,0.005697055,0.002382199,0.0001237828,0.00004416645,0.00001257266,0.0003734651,0.00004793518,0.001104091],"genre_scores_gemma":[0.995334,0.001450742,0.0008338442,0.00005186322,0.000008914055,0.00001739151,0.000356372,0.000004913321,0.001941944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001109746,"threshold_uncertainty_score":0.003712475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490237604082203,"score_gpt":0.2675782024685053,"score_spread":0.2526758264276833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}