{"id":"W2460194638","doi":"10.1097/pgp.0000000000000307","title":"The Chemotherapy Response Score (CRS): Interobserver Reproducibility in a Simple and Prognostically Relevant System for Reporting the Histologic Response to Neoadjuvant Chemotherapy in Tuboovarian High-grade Serous Carcinoma","year":2016,"lang":"en","type":"article","venue":"International Journal of Gynecological Pathology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital","funders":"Academy of Medical Sciences; National Institute for Health and Care Research","keywords":"Medicine; Concordance; Debulking; Chemotherapy; Serous carcinoma; Reproducibility; Radiology; Serous fluid; Response Evaluation Criteria in Solid Tumors; Stage (stratigraphy); Internal medicine; Oncology; Cancer; Progressive disease; Ovarian cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02737647,0.0005775628,0.0006018064,0.004102868,0.0004757157,0.0007052126,0.0006103279,0.0005321134,0.0008634211],"category_scores_gemma":[0.02923996,0.0002848738,0.0007272388,0.001568066,0.0008922193,0.0007173281,0.001500964,0.0003503574,0.0003422042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000411918,"about_ca_system_score_gemma":0.0004332865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001140181,"about_ca_topic_score_gemma":0.003032668,"domain_scores_codex":[0.9802721,0.009397655,0.003382561,0.001562341,0.004982103,0.0004032858],"domain_scores_gemma":[0.9730031,0.01352487,0.004904395,0.00263282,0.005442101,0.0004926903],"domain_codex":null,"domain_gemma":"reproducibility","domain_candidate":"reproducibility","domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001268167,0.00009465634,0.8728523,0.0003208821,0.0005448431,0.0002548429,0.00111905,0.001995959,0.02684724,0.0002676649,0.0008131471,0.09362127],"study_design_scores_gemma":[0.00004489248,0.0006005519,0.9762798,0.00005323402,0.0001566179,0.001246239,0.000367505,0.009410304,0.009724327,0.0003977066,0.001645995,0.00007286199],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.940951,0.001330689,0.05258445,0.0000841122,0.0001245944,0.0004667382,0.0002876271,0.0002612611,0.003909566],"genre_scores_gemma":[0.9688979,0.0001414806,0.02984329,0.00003158084,0.00004850274,0.000182982,0.0003288704,0.00004386561,0.0004815263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9726235,"threshold_uncertainty_score":0.1447823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03915864888086324,"score_gpt":0.321887656237144,"score_spread":0.2827290073562808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}