{"id":"W2460194638","doi":"10.1097/pgp.0000000000000307","title":"The Chemotherapy Response Score (CRS): Interobserver Reproducibility in a Simple and Prognostically Relevant System for Reporting the Histologic Response to Neoadjuvant Chemotherapy in Tuboovarian High-grade Serous Carcinoma","year":2016,"lang":"en","type":"article","venue":"International Journal of Gynecological Pathology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital","funders":"Academy of Medical Sciences; National Institute for Health and Care Research","keywords":"Medicine; Concordance; Debulking; Chemotherapy; Serous carcinoma; Reproducibility; Radiology; Serous fluid; Response Evaluation Criteria in Solid Tumors; Stage (stratigraphy); Internal medicine; Oncology; Cancer; Progressive disease; Ovarian cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.01109793,0.0002095842,0.0006280841,0.0001753103,0.00008359093,0.00003836029,0.000370893,0.0001706221,0.00002451858],"category_scores_gemma":[0.02647796,0.00009225605,0.0001699736,0.0001441301,0.000243938,0.00006327591,0.0001091037,0.0002967535,0.000002160489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001207305,"about_ca_system_score_gemma":0.0002796047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005189531,"about_ca_topic_score_gemma":0.000191209,"domain_scores_codex":[0.9959578,0.0009210783,0.001759596,0.0006875658,0.0003112423,0.000362696],"domain_scores_gemma":[0.9915656,0.006239848,0.001042544,0.000572548,0.0004525231,0.0001269174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1014766,0.001123919,0.794828,0.00002477882,0.0001956123,0.008746322,0.0008773479,0.0000274117,0.02855185,0.0009116622,0.0004857805,0.06275074],"study_design_scores_gemma":[0.007301056,0.004286006,0.9795236,0.0002244041,0.00002985305,0.002642564,0.0001931247,0.00003286544,0.001466283,0.001592429,0.002601711,0.0001061032],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8378623,0.0002702597,0.0003717867,0.1599769,0.000506809,0.0009776644,0.00001280804,0.00001339758,0.000008122915],"genre_scores_gemma":[0.9958229,0.0000981546,0.00165818,0.002006239,0.000158219,0.0001830667,0.000001513861,0.00001912935,0.000052581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1846956,"threshold_uncertainty_score":0.9817224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03915864888086324,"score_gpt":0.321887656237144,"score_spread":0.2827290073562808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}