{"id":"W2460347730","doi":"10.15562/tcp.9","title":"Cancer Gene Therapy to Restore P53 Function: A New Way for an Old Aim","year":2016,"lang":"en","type":"article","venue":"The Cancer Press","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Cancer; Function (biology); Genetic enhancement; Cancer therapy; Computational biology; Cancer research; Biology; Gene; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008435996,0.0001325923,0.0001000073,0.00001449248,0.0001077245,0.00002798396,0.0003075085,0.00006073505,0.0001161532],"category_scores_gemma":[0.00001163001,0.00007130323,0.00006597264,0.00004536627,0.00004211094,0.000007225262,0.0000671534,0.00003389977,0.0000051717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006722041,"about_ca_system_score_gemma":0.0001863245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004819258,"about_ca_topic_score_gemma":0.004541964,"domain_scores_codex":[0.9990709,0.00003607073,0.00009155521,0.0003611072,0.0001309871,0.0003093984],"domain_scores_gemma":[0.9991459,0.00001208644,0.0000349669,0.0005298969,0.00008808495,0.0001891055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003439878,0.00006762646,0.001165189,0.000008613039,0.0003597812,8.397058e-7,0.0001238072,0.00007076981,0.5038899,0.0000819538,0.1217655,0.3690261],"study_design_scores_gemma":[0.002129494,0.0007356924,0.002657034,0.0000191177,0.00002295757,0.000001250202,0.000005105664,0.000005536549,0.4100017,0.0001558152,0.5841355,0.00013087],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9354926,0.04109107,0.00789223,0.01092463,0.001040035,0.002121027,0.0008479694,0.00004804585,0.0005423774],"genre_scores_gemma":[0.9541764,0.009094937,0.0001219308,0.00209519,0.003010488,0.002408341,0.0000409306,0.00005833466,0.02899348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4623699,"threshold_uncertainty_score":0.7285309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06346324208180723,"score_gpt":0.3612818143193628,"score_spread":0.2978185722375556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}