{"id":"W2460523701","doi":"","title":"SHP2 phosphatase promotes mast cell chemotaxis toward stem cell factor via enhancing activation of the Lyn/Vav/Rac signaling axis","year":2014,"lang":"en","type":"article","venue":"PMC","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"LYN; Stem cell factor; Cell biology; Mast cell; Chemotaxis; Phosphorylation; Chemistry; Protein tyrosine phosphatase; Phosphatase; Cancer research; Biology; Stem cell; Receptor; Proto-oncogene tyrosine-protein kinase Src; Immunology; Haematopoiesis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001273688,0.0004438952,0.0001782993,0.0002046752,0.0001682344,0.0002834028,0.0001162268,0.0002130683,0.001401741],"category_scores_gemma":[0.00006916463,0.000129947,0.0002593654,0.00009771978,0.0001716388,0.0001875015,0.0002567973,0.0005195529,0.0002434769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002375959,"about_ca_system_score_gemma":0.0002234315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004809847,"about_ca_topic_score_gemma":0.0009836901,"domain_scores_codex":[0.9998807,0.00002152883,0.000008141286,0.00002118095,0.00003022539,0.00003822801],"domain_scores_gemma":[0.9999458,0.000004955462,0.00001420753,0.000003920564,0.000005519531,0.00002572401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001100792,0.00002327978,0.000159938,0.00003571164,0.000005242181,0.00004445221,0.00000610635,0.00004415472,0.9987414,0.00007437661,0.00005999609,0.0006951324],"study_design_scores_gemma":[0.00003654554,0.0003104422,0.00878809,0.000007340956,0.00002269396,0.0001917473,0.00002931005,0.001709278,0.9861428,0.00005460845,0.002702801,0.000004406046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938689,0.001877692,0.00191205,0.000170941,0.00003456966,0.00002343812,0.0002430305,0.00007447213,0.001794775],"genre_scores_gemma":[0.9959948,0.0008422014,0.000917747,0.00004471107,0.00001432312,0.00003009753,0.0002735768,0.00001125617,0.001871258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001401741,"threshold_uncertainty_score":0.004689336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00936989374899467,"score_gpt":0.2092609659724752,"score_spread":0.1998910722234805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}