{"id":"W2460671595","doi":"10.2217/epi-2016-0022","title":"Responses of Bovine Early Embryos to S-adenosyl Methionine Supplementation in Culture","year":2016,"lang":"en","type":"article","venue":"Epigenomics","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Blastocyst; Epigenetics; DNA methylation; Embryo; Methylation; Methionine; Genetics; Embryogenesis; CpG site; Phenotype; Andrology; Gene; Cell biology; Gene expression; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003925368,0.0000884613,0.000207821,0.0002548532,0.0000232802,0.000007067426,0.00009318035,0.00007100339,0.0003275746],"category_scores_gemma":[0.0002799644,0.00005820652,0.0000457007,0.000263065,0.00003405492,0.00006799283,0.00005328106,0.0000960618,0.0001330883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001334431,"about_ca_system_score_gemma":0.0001119635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002352162,"about_ca_topic_score_gemma":0.0001813465,"domain_scores_codex":[0.9990351,0.00006313586,0.0002823265,0.0001829827,0.0002089328,0.0002274873],"domain_scores_gemma":[0.9994175,0.00009506296,0.00004329585,0.0002263122,0.0001093001,0.0001084745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002586668,0.000126833,0.05648765,0.00004046952,0.00004005056,0.0000374164,0.002144109,0.000001371061,0.9228375,0.00027117,0.003632036,0.01179474],"study_design_scores_gemma":[0.003492142,0.002533229,0.5397142,0.0001632802,0.00003104287,0.00001212969,0.0004206638,0.000009581306,0.4224631,0.000174462,0.03082096,0.0001652428],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942189,0.0001393353,0.0002875828,0.004096419,0.00004502083,0.0004043531,0.00006076416,0.00001233691,0.0007352367],"genre_scores_gemma":[0.980788,0.0002439664,0.002467156,0.0001762562,0.00008271133,0.00001592892,0.00001967932,0.0000170581,0.01618928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5003744,"threshold_uncertainty_score":0.3586712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0318952922526501,"score_gpt":0.3482243421745543,"score_spread":0.3163290499219042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}