{"id":"W2460952910","doi":"10.1088/1742-6596/640/1/012008","title":"Aggregation process of A<i>β</i><sub>1-40</sub>with non-A<i>β</i>amyloid component of<i>α</i>-synuclein","year":2015,"lang":"en","type":"article","venue":"Journal of Physics Conference Series","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Salt bridge; Dimer; Amyloid (mycology); Chemistry; Oligomer; Fibril; Molecular dynamics; Biophysics; Fibrillation; Protein secondary structure; Biochemistry; Biology; Computational chemistry; Medicine; Polymer chemistry; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009152227,0.0001718202,0.0001821037,0.0001858988,0.0004338279,0.0002625423,0.0003064776,0.0003385859,0.001354675],"category_scores_gemma":[0.0002652389,0.0001344904,0.0002954271,0.0001674717,0.0003654884,0.0003264022,0.0002202823,0.0002294549,0.00008148016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003746468,"about_ca_system_score_gemma":0.0003077575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007392006,"about_ca_topic_score_gemma":0.003696523,"domain_scores_codex":[0.9999622,0.000006136981,0.000002002412,0.000006291006,0.00001083485,0.00001246782],"domain_scores_gemma":[0.999896,0.00002737591,0.00003026122,0.000008649148,0.00001719144,0.00002048567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002006667,0.0002704105,0.01264447,0.0001455006,0.0001016337,0.0009206136,0.0002750975,0.9053777,0.06561805,0.008502884,0.0009004092,0.005042593],"study_design_scores_gemma":[0.00001977261,0.0000675708,0.003759682,0.000006446541,0.00001361917,0.00005532151,0.00003784123,0.9905109,0.004423216,0.0008088543,0.0002881892,0.00000858986],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934373,0.0001045875,0.003145421,0.00009027027,0.00001553249,0.00001121134,0.00006701373,0.00004430022,0.003084309],"genre_scores_gemma":[0.997875,0.00006455286,0.00144191,0.00001956792,0.000003239435,0.00001086699,0.00006370856,0.000008935746,0.000512242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007392006,"threshold_uncertainty_score":0.01469797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03534951150792839,"score_gpt":0.2942077801740494,"score_spread":0.258858268666121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}