{"id":"W2461217232","doi":"10.1177/1073110516654133","title":"Screening of Newborns for Disorders with High Benefit-Risk Ratios Should Be Mandatory","year":2016,"lang":"en","type":"article","venue":"The Journal of Law Medicine & Ethics","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Newborn Screening Ontario","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Medicine; Newborn screening; Pediatrics; Psychiatry; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002015391,0.0001405274,0.0002689511,0.00003581828,0.0001226279,0.000003694891,0.0003170122,0.0001525181,0.0000282609],"category_scores_gemma":[0.0004768842,0.00006320237,0.00007737952,0.00005348216,0.0005810289,0.000007199061,0.00003894233,0.0002675478,1.880616e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002132802,"about_ca_system_score_gemma":0.0001206657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001245958,"about_ca_topic_score_gemma":0.0006602095,"domain_scores_codex":[0.998766,0.0001458962,0.0004061039,0.0001134018,0.0003938456,0.0001747732],"domain_scores_gemma":[0.9984177,0.0003572056,0.0005036442,0.0003022521,0.0003339761,0.00008521541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01249604,0.0004780517,0.01407758,0.0005366211,0.002670223,0.000006559932,0.01257947,0.00368706,0.7061096,0.07412156,0.02896834,0.1442689],"study_design_scores_gemma":[0.01756659,0.009066401,0.008026644,0.0009508444,0.001908732,0.00009172368,0.003939061,0.00003212233,0.1348666,0.01779012,0.805152,0.000609205],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6778304,0.006182409,0.2714166,0.0426251,0.0004500929,0.0004229227,0.0000789133,0.000005618314,0.0009879369],"genre_scores_gemma":[0.9883297,0.005704225,0.003055683,0.002135399,0.0004894482,0.00000345218,0.000009342007,0.00002622762,0.0002465206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7761837,"threshold_uncertainty_score":0.2577318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04547612181502979,"score_gpt":0.3209602978835548,"score_spread":0.275484176068525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}