{"id":"W2461561997","doi":"10.1016/j.ymgme.2016.06.010","title":"Physical therapy management of infants and children with hypophosphatasia","year":2016,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Alkaline Phosphatase Research Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre","funders":"","keywords":"Hypophosphatasia; Medicine; Enzyme replacement therapy; Disease; Pediatrics; Rickets; Physical therapy; Osteomalacia; Muscle weakness; Natural history; Metabolic bone disease; Intensive care medicine; Vitamin D and neurology; Osteoporosis; Internal medicine; Alkaline phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001458759,0.0002039659,0.0003422368,0.0003702519,0.0003809475,0.0002203907,0.0001798341,0.0003881621,0.0009293974],"category_scores_gemma":[0.001298193,0.00007275783,0.0001916956,0.0002862244,0.0001679406,0.0001249155,0.0002478673,0.0004229941,0.00009518254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003273745,"about_ca_system_score_gemma":0.0005163776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00223587,"about_ca_topic_score_gemma":0.003186757,"domain_scores_codex":[0.9998726,0.0000368189,0.00001512882,0.000007713586,0.00003424007,0.00003356296],"domain_scores_gemma":[0.9998571,0.00004374137,0.00003974369,0.000002350456,0.00001205988,0.00004512673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008007894,0.0008318075,0.8056618,0.0004644892,0.00009993513,0.06849574,0.001488583,0.0003963216,0.004856577,0.0005589846,0.003182893,0.1131621],"study_design_scores_gemma":[0.00003714065,0.001071704,0.9486027,0.0002933732,0.00005038643,0.04448555,0.001497182,0.0002210781,0.0006176328,0.000244191,0.002870786,0.000008268412],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794074,0.01170399,0.0001792169,0.001169353,0.00005346755,0.00003020055,0.00008515927,0.00001127256,0.007360021],"genre_scores_gemma":[0.9924436,0.006126802,0.0003178279,0.0001706262,0.00004454443,0.00002989573,0.0001007079,0.000001989531,0.0007639489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00223587,"threshold_uncertainty_score":0.004445732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008956467730835778,"score_gpt":0.272839990719417,"score_spread":0.2638835229885812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}