{"id":"W2461699721","doi":"10.1371/journal.pone.0157550","title":"Whole Blood Gene Expression Differentiates between Atrial Fibrillation and Sinus Rhythm after Cardioversion","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton General Hospital; Hamilton Health Sciences; Thrombosis and Atherosclerosis Research Institute; McMaster University; Population Health Research Institute","funders":"Mach-Gaensslen Foundation of Canada; Freiwillige Akademische Gesellschaft; Universität Basel; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Cardioversion; Sinus rhythm; Medicine; Atrial fibrillation; Internal medicine; PDK4; Cardiology; Pathophysiology; Natriuretic peptide; Biomarker; Area under the curve; Gene expression; Heart failure; Gene; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002958945,0.0002092858,0.0003612508,0.0004518097,0.00009095588,0.0005376391,0.00008661322,0.0002917804,0.0009631495],"category_scores_gemma":[0.00110101,0.00008244863,0.0002373,0.0004109292,0.0002150019,0.0001728242,0.0001464074,0.0002227326,0.0002431431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001508744,"about_ca_system_score_gemma":0.00009383292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002872087,"about_ca_topic_score_gemma":0.0003829154,"domain_scores_codex":[0.9997848,0.00005272304,0.00002122939,0.00007470138,0.00004031966,0.00002636709],"domain_scores_gemma":[0.9993812,0.000290469,0.0001623414,0.0000435658,0.00005534718,0.00006694328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00209192,0.00007669521,0.9380563,0.00006656122,0.0001436266,0.0001259414,0.00009513139,0.0004556197,0.03991004,0.00003958774,0.0002300535,0.01870845],"study_design_scores_gemma":[0.00001908551,0.0003708346,0.994093,0.000008397442,0.00005906178,0.0004716882,0.00006998359,0.001281095,0.003300834,0.0001075917,0.0002124981,0.000005956797],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986615,0.0003390134,0.0003711538,0.00002623246,0.000007240159,0.000005550613,0.00028871,0.00001027839,0.0002902898],"genre_scores_gemma":[0.9988332,0.0001395731,0.0003365774,0.00002947675,0.000009260306,0.000012631,0.0004906086,0.000003181561,0.0001454368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009631495,"threshold_uncertainty_score":0.003222048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05022336895792445,"score_gpt":0.2560087593188057,"score_spread":0.2057853903608812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}