{"id":"W2461842986","doi":"10.1016/j.molmet.2016.06.006","title":"Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice","year":2016,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Directorate for Biological Sciences; Novo Nordisk Fonden; Sahlgrenska Universitetssjukhuset; Västra Götalandsregionen; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning; IngaBritt och Arne Lundbergs Forskningsstiftelse; European Research Council; Torsten Söderbergs Stiftelse; Biotechnology and Biological Sciences Research Council; Svenska Forskningsrådet Formas","keywords":"Glucagon-like peptide-1; Glucagon; Peptide; Glucagon-like peptide-2; Internal medicine; Endocrinology; Chemistry; Diabetes mellitus; Biology; Biochemistry; Medicine; Insulin; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003554049,0.001135159,0.0006180945,0.000842583,0.0002086966,0.0005684225,0.0004980588,0.0007729679,0.001937775],"category_scores_gemma":[0.0002296024,0.0002929293,0.0005218899,0.0003524154,0.0004291974,0.0005977452,0.0003233659,0.001971894,0.0006623549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004175933,"about_ca_system_score_gemma":0.0003241635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002691248,"about_ca_topic_score_gemma":0.0003718766,"domain_scores_codex":[0.9996573,0.00005628581,0.00003753787,0.00008304838,0.00008487783,0.00008102111],"domain_scores_gemma":[0.999532,0.00003124916,0.0002100177,0.00003951402,0.00002755613,0.000159706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001303225,0.0005727517,0.0002774279,0.00009571126,0.00001561285,0.00005945319,0.0000176888,0.0000851626,0.9940352,0.0000620422,0.0001236599,0.003352063],"study_design_scores_gemma":[0.0006046905,0.008859069,0.008106668,0.00006578633,0.00009179433,0.0004312154,0.00007497388,0.001170641,0.976178,0.0001188132,0.0042764,0.00002196175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912912,0.00219631,0.002480331,0.0005193936,0.0001768597,0.00006789932,0.001036185,0.0005302157,0.001701533],"genre_scores_gemma":[0.9832153,0.002540438,0.005405216,0.0004742004,0.00008759244,0.0002019186,0.001942134,0.0001656362,0.005967623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001937775,"threshold_uncertainty_score":0.006482482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006171070613708712,"score_gpt":0.2233760585971283,"score_spread":0.2172049879834196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}