{"id":"W2461842986","doi":"10.1016/j.molmet.2016.06.006","title":"Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice","year":2016,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Directorate for Biological Sciences; Novo Nordisk Fonden; Sahlgrenska Universitetssjukhuset; Västra Götalandsregionen; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning; IngaBritt och Arne Lundbergs Forskningsstiftelse; European Research Council; Torsten Söderbergs Stiftelse; Biotechnology and Biological Sciences Research Council; Svenska Forskningsrådet Formas","keywords":"Glucagon-like peptide-1; Glucagon; Peptide; Glucagon-like peptide-2; Internal medicine; Endocrinology; Chemistry; Diabetes mellitus; Biology; Biochemistry; Medicine; Insulin; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002016772,0.0002724876,0.0004477021,0.0002014069,0.00002994141,0.00002723384,0.0001670168,0.0000605545,0.0000485049],"category_scores_gemma":[0.00007544427,0.0001886583,0.0001570178,0.0002666726,0.00005805341,0.0001311333,0.0001005421,0.00008928501,0.0001999957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006771021,"about_ca_system_score_gemma":0.00007459208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006444531,"about_ca_topic_score_gemma":0.00002261056,"domain_scores_codex":[0.9983476,0.00005760403,0.0003166263,0.0005473062,0.0002430863,0.0004877273],"domain_scores_gemma":[0.9991609,0.00001779317,0.00008407879,0.0005339927,0.00007359766,0.0001296243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000141291,0.0002948165,0.0004317224,0.00004976489,0.0001293244,0.0001775414,0.00009571773,0.00000147811,0.9556822,0.0006022155,0.0009252314,0.04146867],"study_design_scores_gemma":[0.0047947,0.00007648688,0.03201577,0.0001630987,0.0002497171,0.000007279148,0.0000145477,0.000007955572,0.8339956,0.0001458768,0.1282661,0.0002628953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894667,0.004188235,0.0002509109,0.002399621,0.0004704145,0.0009296242,0.000006036245,0.00009355103,0.002194941],"genre_scores_gemma":[0.9868534,0.0002913578,0.002839496,0.002400923,0.0001383808,0.0001317324,0.00001713888,0.0000557506,0.007271825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1273408,"threshold_uncertainty_score":0.7693264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006171070613708712,"score_gpt":0.2233760585971283,"score_spread":0.2172049879834196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}