{"id":"W2462678394","doi":"10.1182/blood.v120.21.2534.2534","title":"NPM1, IDH1/2 and DNAH11 Gene Mutations Can Improve a Prognostic Stratification of Acute Myeloid Leukemia Patients with Normal Karyotype but Not Harboring FLT3/ITD Mutation.","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"NPM1; Myeloid leukemia; Internal medicine; Oncology; IDH1; Neuroblastoma RAS viral oncogene homolog; Biology; Sanger sequencing; Myeloid; Cancer research; Immunology; Medicine; Mutation; Karyotype; Gene; Genetics; KRAS","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004039222,0.0002348398,0.0002252223,0.0004563359,0.0001875201,0.0002603939,0.0001782363,0.0002295625,0.001554833],"category_scores_gemma":[0.001076359,0.00007875177,0.0001490838,0.0002829396,0.0001390096,0.0002057308,0.0002618486,0.0002666375,0.0003004719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001631698,"about_ca_system_score_gemma":0.0001491283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005135569,"about_ca_topic_score_gemma":0.0008436044,"domain_scores_codex":[0.999884,0.00003077521,0.00001380751,0.0000320719,0.00001812414,0.00002115163],"domain_scores_gemma":[0.9996396,0.0001316091,0.0000747181,0.00002760884,0.00003720256,0.00008928568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000899002,0.00003547422,0.9865283,0.00001006189,0.00002434508,0.0001057298,0.00003006733,0.0001532217,0.004491436,0.00001672267,0.000141675,0.007563815],"study_design_scores_gemma":[0.00004198265,0.0003438928,0.9938997,0.000007410569,0.00004649246,0.0008433576,0.00005702408,0.001885678,0.002240583,0.00009465846,0.0005352066,0.000004170326],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992663,0.0001571945,0.000189701,0.00003198394,0.000003237082,0.00000707109,0.0001553114,0.000005838924,0.0001834867],"genre_scores_gemma":[0.9991862,0.00004668923,0.0002857728,0.000008100561,0.000006669971,0.000005529015,0.0003483873,0.0000014724,0.0001111062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001554833,"threshold_uncertainty_score":0.005201459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068870639076031,"score_gpt":0.2449127783885928,"score_spread":0.2342240719978325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}