{"id":"W2463330250","doi":"10.1371/journal.ppat.1005684","title":"Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Crohn's and Colitis Foundation; Crohn's and Colitis Foundation of America; Eli and Edythe Broad Foundation; Cancer Research Institute; American Cancer Society","keywords":"Biology; Acquired immune system; Immune system; Viral replication; Virology; Immunology; Immunity; T cell; Dendritic cell; CD11c; Innate immune system; Interferon; CD8; Virus; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002533379,0.0003769824,0.0003778738,0.0002697678,0.0001207243,0.0004795543,0.0002573119,0.0004606305,0.001134136],"category_scores_gemma":[0.0003831612,0.000232981,0.0002287585,0.0001179574,0.0003582448,0.000246724,0.0002922333,0.001202328,0.000375437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004478184,"about_ca_system_score_gemma":0.0003641998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004363267,"about_ca_topic_score_gemma":0.0005994467,"domain_scores_codex":[0.9995407,0.00009312105,0.00005569885,0.00009016224,0.00008105626,0.0001393387],"domain_scores_gemma":[0.9992465,0.0001528308,0.0002299826,0.0001123627,0.00004726456,0.0002110653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001826149,0.00006645885,0.0003798638,0.00002171547,0.000003986888,0.0001080473,0.00001040709,0.00005804936,0.9984272,0.00008739884,0.00003983895,0.0006145287],"study_design_scores_gemma":[0.0001712771,0.001571869,0.009825023,0.0000296262,0.00004473346,0.001946874,0.00008188455,0.002274117,0.981636,0.0001793591,0.002225647,0.00001359711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973738,0.0005170436,0.0009868464,0.0001220023,0.00003435718,0.00002230175,0.0002426371,0.00007127133,0.0006297103],"genre_scores_gemma":[0.997234,0.0003129683,0.000811421,0.00006091598,0.00001514282,0.00002330737,0.000257244,0.00002946935,0.001255583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001134136,"threshold_uncertainty_score":0.003794014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05476992918920026,"score_gpt":0.2778992001002959,"score_spread":0.2231292709110956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}