{"id":"W2463997993","doi":"10.1038/srep28295","title":"Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Research Foundation of Korea; National Research Foundation","keywords":"MECP2; Phosphorylation; Chromatin; Biology; Serine; Epigenetics; Cell biology; Acetylation; Histone; Rett syndrome; Neuroscience; Genetics; DNA; Phenotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007040222,0.0002972125,0.0001408271,0.0001790636,0.00009303063,0.0001817663,0.0001587477,0.000139223,0.001468518],"category_scores_gemma":[0.0001195353,0.0001219088,0.0001788387,0.00009234661,0.0002617093,0.0001312575,0.0002082314,0.0002996004,0.0002401281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002224062,"about_ca_system_score_gemma":0.0001655822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003986056,"about_ca_topic_score_gemma":0.0006756365,"domain_scores_codex":[0.9999362,0.000009042991,0.000005686582,0.00001988348,0.00001220645,0.00001694891],"domain_scores_gemma":[0.9999167,0.000009575174,0.00003994571,0.000007058917,0.000005765811,0.00002108811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001230255,0.000007615076,0.000408024,0.00001869722,0.000005641768,0.00008537754,0.000007594348,0.00002244298,0.9982647,0.00006258321,0.00001932542,0.0009749556],"study_design_scores_gemma":[0.00001261187,0.0002116874,0.03651296,0.000007776465,0.00002318117,0.0009490272,0.00004108058,0.0004269301,0.9603475,0.0001691107,0.001291208,0.000006963503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970589,0.001141259,0.0009026933,0.00005628521,0.00001394151,0.000005249379,0.0001784023,0.00003236448,0.0006109027],"genre_scores_gemma":[0.9970232,0.0006073159,0.0006522587,0.00003343433,0.000005934538,0.00001255763,0.0002982548,0.00001457284,0.001352594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001468518,"threshold_uncertainty_score":0.004912674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005433293348991782,"score_gpt":0.2096535466289884,"score_spread":0.2042202532799967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}