{"id":"W2464061075","doi":"10.3899/jrheum.160064","title":"Canakinumab for Childhood Sight-threatening Refractory Uveitis: A Case Series","year":2016,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Canakinumab; Medicine; Refractory (planetary science); Uveitis; Dermatology; Familial Mediterranean fever; Arthritis; Anakinra; Pediatrics; Immunology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007082654,0.0021949,0.002027215,0.002415941,0.002535521,0.001855553,0.001880322,0.008887121,0.003461439],"category_scores_gemma":[0.005186292,0.0009736847,0.001535906,0.00210299,0.001944903,0.002558306,0.001371583,0.004633798,0.001156856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002111793,"about_ca_system_score_gemma":0.0009197719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001591514,"about_ca_topic_score_gemma":0.002674177,"domain_scores_codex":[0.9987636,0.0002037574,0.0001696891,0.0002376112,0.0002250031,0.0004003692],"domain_scores_gemma":[0.9957286,0.001830655,0.0007943648,0.0002779119,0.0002554672,0.001113094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00002755568,0.00002581842,0.001927292,0.00005319856,0.00001300498,0.994931,0.0001053493,0.00004260689,0.0001914625,0.0001631083,0.001386545,0.001132912],"study_design_scores_gemma":[0.00002626328,0.00003704644,0.002044397,0.00003974049,0.00002514954,0.995479,0.0001146315,0.0002184391,0.0001741059,0.0001376689,0.001695602,0.000008007823],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8071816,0.06650224,0.005668474,0.07026979,0.0129981,0.0003711671,0.0004662368,0.0006264787,0.03591589],"genre_scores_gemma":[0.9607357,0.009232337,0.001854289,0.0092,0.01423254,0.00005397169,0.000138515,0.00007716694,0.004475411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008887121,"threshold_uncertainty_score":0.01532221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01879152883421591,"score_gpt":0.28042031977506,"score_spread":0.2616287909408441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}