{"id":"W2464209936","doi":"10.1093/rpd/ncw160","title":"THE EFFECT OF AN OPTIMIZED IMAGING FLOW CYTOMETRY ANALYSIS TEMPLATE ON SAMPLE THROUGHPUT IN THE REDUCED CULTURE CYTOKINESIS-BLOCK MICRONUCLEUS ASSAY","year":2016,"lang":"en","type":"article","venue":"Radiation Protection Dosimetry","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Micronucleus test; Micronucleus; Binucleated cells; Flow cytometry; Nuclear medicine; Computer science; Biomedical engineering; Chemistry; Biology; Medicine; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007434014,0.001848158,0.001707388,0.001343532,0.0006409382,0.002379328,0.001814564,0.001674869,0.002812878],"category_scores_gemma":[0.01632899,0.001265229,0.001068998,0.001135874,0.0008614915,0.00147247,0.001306515,0.00211082,0.001998014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001016701,"about_ca_system_score_gemma":0.001224263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001980846,"about_ca_topic_score_gemma":0.003280015,"domain_scores_codex":[0.9904219,0.001945,0.001060854,0.002152729,0.003852705,0.0005669377],"domain_scores_gemma":[0.9880905,0.007301556,0.0009050799,0.00115795,0.002218496,0.0003264125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006584493,0.000361017,0.001800549,0.0004584774,0.00008186008,0.0001845426,0.0003283036,0.002329977,0.969476,0.0005015853,0.001602758,0.02221649],"study_design_scores_gemma":[0.00004756193,0.0005063649,0.004240617,0.00004735252,0.0001333617,0.0002715328,0.00006692861,0.01808478,0.969067,0.0002222012,0.007229548,0.00008286781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4194358,0.004448985,0.5500498,0.002333724,0.001262498,0.003511096,0.002903735,0.01166462,0.004389609],"genre_scores_gemma":[0.2887615,0.001775892,0.6943734,0.0009130769,0.0002761606,0.004124586,0.003619324,0.00201793,0.004138121],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007434014,"threshold_uncertainty_score":0.03931528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005797693504974439,"score_gpt":0.2637773494978261,"score_spread":0.2579796559928516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}