{"id":"W2464790280","doi":"10.1139/cjpp-2015-0566","title":"The investigation of the cellular electrophysiological and antiarrhythmic effects of a novel selective sodium–calcium exchanger inhibitor, GYKB-6635, in canine and guinea-pig hearts","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hungarian Scientific Research Fund","keywords":"Sodium-calcium exchanger; Repolarization; Electrophysiology; Chemistry; Ouabain; Calcium; Depolarization; Pharmacology; Guinea pig; Patch clamp; Membrane potential; Sodium; Cardiac electrophysiology; Sodium channel; Biophysics; Ventricular fibrillation; Cardiac action potential; Internal medicine; Medicine; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000172913,0.0004354444,0.0004725793,0.000171969,0.00009951571,0.0001875422,0.000252736,0.0003101459,0.0005557053],"category_scores_gemma":[0.000113273,0.0001432282,0.0002738412,0.0001073171,0.0001899431,0.0002163047,0.0001195037,0.0007028891,0.0001590106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001117941,"about_ca_system_score_gemma":0.0001501848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004052302,"about_ca_topic_score_gemma":0.000658005,"domain_scores_codex":[0.9999429,0.000007641362,0.000006405015,0.00001361646,0.00001322575,0.00001620579],"domain_scores_gemma":[0.9999399,0.00001046657,0.00001736386,0.000005869958,0.000007393805,0.00001895222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001212027,0.00002553452,0.00005219848,0.00006434057,0.000006939967,0.00003663174,0.00000965549,0.00002664634,0.9986023,0.00002356592,0.00001759396,0.001013493],"study_design_scores_gemma":[0.000118443,0.003572354,0.009414897,0.00001893855,0.0001327617,0.0004447439,0.00003783755,0.0007668033,0.9833785,0.00002892801,0.002077374,0.000008508883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904464,0.006735616,0.001487895,0.0000828468,0.00004380596,0.00003661137,0.000179163,0.00005717413,0.0009305083],"genre_scores_gemma":[0.9909856,0.005184273,0.002094077,0.0000700973,0.0000240835,0.00003117073,0.0004275822,0.000014892,0.001168154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005557053,"threshold_uncertainty_score":0.001859009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009892707817736648,"score_gpt":0.2401430640974427,"score_spread":0.2302503562797061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}