{"id":"W2465612624","doi":"10.1097/qad.0000000000001098","title":"Three months of weekly rifapentine and isoniazid for treatment of Mycobacterium tuberculosis infection in HIV-coinfected persons","year":2016,"lang":"en","type":"article","venue":"AIDS","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":163,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cilag; National Institute of Allergy and Infectious Diseases; Centers for Disease Control and Prevention; National Institutes of Health; International Maternal Pediatric Adolescent AIDS Clinical Trials Network; ViiV Healthcare; Gilead Sciences; Centers for Disease Control and Prevention Foundation; Sanofi; ACT Government; U.S. Food and Drug Administration; Bristol-Myers Squibb","keywords":"Tolerability; Medicine; Isoniazid; Rifapentine; Tuberculosis; Discontinuation; Internal medicine; Adverse effect; Clinical endpoint; Surgery; Randomized controlled trial; Mycobacterium tuberculosis; Latent tuberculosis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00148921,0.0004177243,0.001463086,0.000187844,0.0003030193,0.0004028184,0.0004109026,0.0008458219,0.001884443],"category_scores_gemma":[0.001440208,0.0002910536,0.001047151,0.0002127804,0.0003283998,0.0003989099,0.0002701828,0.001338355,0.0002404142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002472935,"about_ca_system_score_gemma":0.0004666034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006111751,"about_ca_topic_score_gemma":0.001175113,"domain_scores_codex":[0.9993047,0.0003594473,0.00007183284,0.0001098541,0.00006994976,0.00008426712],"domain_scores_gemma":[0.9989173,0.0002840368,0.0004189477,0.0000584366,0.00005224529,0.0002690407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8564711,0.01367311,0.01059575,0.001392709,0.00146304,0.0000902313,0.0001180881,0.0006152575,0.004462048,0.00004649057,0.0003430928,0.1107291],"study_design_scores_gemma":[0.4449543,0.4795885,0.06983751,0.0002017355,0.001492129,0.0002051129,0.00007375789,0.0008972384,0.001820596,0.0001103342,0.0007955607,0.00002318528],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995082,0.003638725,0.0002029065,0.0001155569,0.00007312084,0.0003794,0.0001137039,0.00001913801,0.0003753887],"genre_scores_gemma":[0.9975568,0.001063653,0.0003937504,0.0001542252,0.0001042183,0.000338649,0.0001108049,0.000002178716,0.0002757196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001884443,"threshold_uncertainty_score":0.0078758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02457623296473886,"score_gpt":0.3087647224573848,"score_spread":0.2841884894926459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}