{"id":"W2465612624","doi":"10.1097/qad.0000000000001098","title":"Three months of weekly rifapentine and isoniazid for treatment of Mycobacterium tuberculosis infection in HIV-coinfected persons","year":2016,"lang":"en","type":"article","venue":"AIDS","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":163,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cilag; National Institute of Allergy and Infectious Diseases; Centers for Disease Control and Prevention; National Institutes of Health; International Maternal Pediatric Adolescent AIDS Clinical Trials Network; ViiV Healthcare; Gilead Sciences; Centers for Disease Control and Prevention Foundation; Sanofi; ACT Government; U.S. Food and Drug Administration; Bristol-Myers Squibb","keywords":"Tolerability; Medicine; Isoniazid; Rifapentine; Tuberculosis; Discontinuation; Internal medicine; Adverse effect; Clinical endpoint; Surgery; Randomized controlled trial; Mycobacterium tuberculosis; Latent tuberculosis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002237909,0.0001251136,0.0005186647,0.0002248667,0.00002045804,0.000002144649,0.00002684792,0.0001063006,0.00008687797],"category_scores_gemma":[0.0004714048,0.0000775097,0.0001317956,0.0001577165,0.0001151253,0.00006844661,0.00002113481,0.00003361451,0.000006159826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008781126,"about_ca_system_score_gemma":0.00004665328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001898181,"about_ca_topic_score_gemma":0.0007129349,"domain_scores_codex":[0.9990368,0.00005830106,0.0003208469,0.0002185225,0.00009224375,0.0002732209],"domain_scores_gemma":[0.9991133,0.0003987286,0.00008115938,0.0002083657,0.0000965369,0.0001018597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005145389,0.0003426335,0.8361701,0.0001186262,0.000152534,0.00000194226,0.00009119977,3.765511e-7,0.13897,0.000162313,0.0005296878,0.02294604],"study_design_scores_gemma":[0.004657757,0.00464982,0.9606812,0.0001321537,0.0001212019,0.00001435384,0.00001757558,0.0001767338,0.0273924,0.0001564774,0.001924856,0.00007545694],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949989,0.0003167575,0.0007141599,0.002984195,0.00004827577,0.0005960732,0.00007243114,0.00001733924,0.0002518197],"genre_scores_gemma":[0.9974198,0.001296653,0.0008428825,0.00003443805,0.00006448744,0.0001139512,0.0000238878,0.00001442413,0.0001895231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1245111,"threshold_uncertainty_score":0.3160754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02457623296473886,"score_gpt":0.3087647224573848,"score_spread":0.2841884894926459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}