{"id":"W2465703708","doi":"10.1002/cmdc.201600213","title":"Synthesis and Biological Evaluation of Iodoglucoazomycin (I‐GAZ), an Azomycin–Glucose Adduct with Putative Applications in Diagnostic Imaging and Radiotherapy of Hypoxic Tumors","year":2016,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates - Health Solutions; University of Melbourne; Alberta Cancer Foundation","keywords":"Chemistry; Adduct; Biodistribution; Glucose transporter; Excretion; Radiochemistry; Biochemistry; Internal medicine; In vitro; Medicine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004719527,0.0001544248,0.0002679068,0.00006774431,0.00002631731,0.000005686498,0.00009340933,0.00007546306,0.00001267617],"category_scores_gemma":[0.0005598421,0.0001040352,0.00003117009,0.000113826,0.0003503753,0.0000120107,0.00003431088,0.00004037389,1.809743e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002134127,"about_ca_system_score_gemma":0.00009772612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003702714,"about_ca_topic_score_gemma":0.00002754769,"domain_scores_codex":[0.9989806,0.00009832186,0.0002474319,0.0003684525,0.0001394613,0.0001657791],"domain_scores_gemma":[0.9991301,0.000248028,0.0001596176,0.0002400425,0.0001422068,0.00007994955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008709549,0.00009111073,0.01790929,0.00002510652,0.00003083657,2.612206e-7,0.0002115331,0.000003742885,0.9049043,0.00004240228,0.00002809273,0.07666623],"study_design_scores_gemma":[0.001260636,0.0001093438,0.05870836,0.0000572468,0.00005545166,0.00001437675,0.0003591661,0.00006314062,0.9384893,0.0002509641,0.0004801649,0.0001518441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986261,0.01237244,0.000705453,0.0000908224,0.0000221822,0.0004067397,0.00005033855,0.000007366704,0.00008372273],"genre_scores_gemma":[0.9951729,0.003223619,0.00118865,0.0000253402,0.0001271262,0.0002089119,0.0000272198,0.00001676983,0.000009436627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07651439,"threshold_uncertainty_score":0.4242432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772522306478835,"score_gpt":0.2734123278387845,"score_spread":0.2556871047739961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}