{"id":"W2465950145","doi":"10.1074/jbc.m116.741256","title":"Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Biotechnology and Biological Sciences Research Council; Seventh Framework Programme; University of Tokyo; European Commission","keywords":"Lipid A; Lipopolysaccharide; Biology; Syk; Antigen; TLR4; Glycan; Toll-like receptor; Microbiology; Molecular biology; Receptor; Tyrosine kinase; Innate immune system; Glycoprotein; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003718351,0.0001391217,0.0003169211,0.00002943387,0.00004802696,0.000005221465,0.0001836306,0.0001931868,0.00005648421],"category_scores_gemma":[0.0007188129,0.00008448778,0.0001200331,0.00005704982,0.0002687018,0.00000583164,0.0001569122,0.0001140238,3.570657e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001743969,"about_ca_system_score_gemma":0.00006640566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003722922,"about_ca_topic_score_gemma":6.255635e-7,"domain_scores_codex":[0.9988818,0.00006240066,0.0005120302,0.0001863564,0.0001717502,0.0001856614],"domain_scores_gemma":[0.9986972,0.00008385741,0.000593071,0.0001497096,0.0003654991,0.0001106642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001697844,0.0001068287,0.01171911,0.00005757409,0.0001471702,0.000005295628,0.00001127114,3.255714e-7,0.9858913,0.000003399023,0.0001219008,0.001766011],"study_design_scores_gemma":[0.0005440447,0.0005752502,0.006996513,0.00009633362,0.00002302693,0.00001756977,0.00007907232,0.000001163912,0.9912234,0.0001063329,0.0002345534,0.0001027653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991304,0.0002231961,0.0002047793,0.0000805794,0.00003214656,0.00006431792,0.00003890651,0.000002994154,0.0002226979],"genre_scores_gemma":[0.9978374,0.001440798,0.0004008136,0.00001688799,0.0001134661,0.000002197248,0.000008460803,0.00000840275,0.0001715698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005332041,"threshold_uncertainty_score":0.3445312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03753877610559284,"score_gpt":0.2914010454542835,"score_spread":0.2538622693486906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}