{"id":"W2466574476","doi":"10.1021/acsnano.6b04308","title":"Local Affinity Release","year":2016,"lang":"en","type":"article","venue":"ACS Nano","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Self-healing hydrogels; Drug delivery; Nanotechnology; Controlled release; Small molecule; Materials science; Drug; Biocompatible material; Site of action; Biophysics; Chemistry; Biomedical engineering; Pharmacology; Biochemistry; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005848926,0.001003426,0.0006074787,0.0005830647,0.0004468258,0.001108567,0.0005684916,0.0007054157,0.01569916],"category_scores_gemma":[0.0005263268,0.000335419,0.0005622491,0.0004002539,0.0003779709,0.0008768849,0.0008724985,0.001153725,0.01362601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000802365,"about_ca_system_score_gemma":0.0005650207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005121339,"about_ca_topic_score_gemma":0.0007600938,"domain_scores_codex":[0.9993089,0.00006208329,0.00005325551,0.0002130367,0.0002509336,0.0001118492],"domain_scores_gemma":[0.9997061,0.00005567938,0.00006229055,0.00005663533,0.00008648071,0.00003276542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001552874,0.00008671859,0.0001810372,0.0006300639,0.00002870307,0.0002350344,0.00009912646,0.000466726,0.9228886,0.002892822,0.005295454,0.06704046],"study_design_scores_gemma":[0.00005958196,0.0005090785,0.0008507073,0.00007872338,0.00004121796,0.0006253253,0.00004960742,0.001603575,0.8876232,0.0004447466,0.1080694,0.0000448053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2501644,0.08246037,0.3626795,0.002992937,0.002974175,0.00328436,0.006047369,0.00935743,0.2800395],"genre_scores_gemma":[0.7047303,0.02216576,0.05005871,0.002715832,0.0004939844,0.001579632,0.003047537,0.0009874178,0.2142209],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01569916,"threshold_uncertainty_score":0.0525189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0123563622947625,"score_gpt":0.24316061280475,"score_spread":0.2308042505099875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}