{"id":"W2466606494","doi":"10.1038/srep29502","title":"Conformational Heterogeneity of Bax Helix 9 Dimer for Apoptotic Pore Formation","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Science Foundation","keywords":"Dimer; Helix (gastropod); Apoptosis; Biophysics; Chemistry; Cell biology; Conformational change; Biology; Biochemistry; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001276247,0.0001740001,0.0001436099,0.00008431455,0.0004848377,0.0002750273,0.000256777,0.000223734,0.001386836],"category_scores_gemma":[0.0002687348,0.0001465857,0.0001995373,0.00006340672,0.0002517574,0.0004643108,0.0002077561,0.0003400464,0.0002279309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002961386,"about_ca_system_score_gemma":0.0003887958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000514339,"about_ca_topic_score_gemma":0.000666258,"domain_scores_codex":[0.9999503,0.00001317758,0.000002200997,0.0000104804,0.00001067841,0.00001318565],"domain_scores_gemma":[0.9999313,0.0000182257,0.00001324309,0.000007137504,0.00001182659,0.0000182401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007959886,0.0003321471,0.007228941,0.0001579007,0.00004356106,0.0006351951,0.0002924009,0.06346665,0.9080179,0.01402721,0.0005570495,0.00444505],"study_design_scores_gemma":[0.000271425,0.0006156557,0.009971341,0.00003936841,0.0001114144,0.0004188633,0.0007845678,0.5601023,0.4143832,0.01069148,0.002521387,0.00008907117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995625,0.00009651436,0.003257666,0.00007208723,0.000009004225,0.000007207186,0.00003039439,0.00002654185,0.0008756808],"genre_scores_gemma":[0.9989766,0.00006396717,0.0007263877,0.0000105895,0.0000013403,0.00000630491,0.0000455281,0.000005583135,0.0001637146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001386836,"threshold_uncertainty_score":0.004639387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01338936924761272,"score_gpt":0.2615468083737482,"score_spread":0.2481574391261355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}