{"id":"W2466706764","doi":"10.1021/acs.molpharmaceut.6b00358","title":"Long-Term Sustained Release from a Biodegradable Photo-Cross-Linked Network for Intraocular Corticosteroid Delivery","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmaceutics","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Ethylene glycol; Triamcinolone acetonide; Trimethylene carbonate; Corticosteroid; Ethylene carbonate; Controlled release; Dexamethasone; Chemistry; PLGA; Lactide; Materials science; Polymer; Pharmacology; Medicine; Surgery; In vitro; Copolymer; Organic chemistry; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001890028,0.0002330116,0.0001124806,0.0001396275,0.0001087611,0.00023303,0.0001343871,0.0002699392,0.0006115079],"category_scores_gemma":[0.0001883718,0.0001030815,0.0001372197,0.00009233304,0.0001442274,0.0002973384,0.0001049685,0.0002620863,0.0002107566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002460742,"about_ca_system_score_gemma":0.0001938968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003789623,"about_ca_topic_score_gemma":0.0008337751,"domain_scores_codex":[0.9999139,0.00001452568,0.00000577585,0.00001876408,0.00003239626,0.00001458755],"domain_scores_gemma":[0.9998879,0.00002830968,0.00004509973,0.000007327347,0.00001127534,0.0000200336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002609937,0.00001269495,0.00003387434,0.00002117895,0.000001231022,0.00002291424,0.000006729407,0.00006394531,0.9982409,0.00002848056,0.000007923684,0.001534054],"study_design_scores_gemma":[0.00001644916,0.0006505811,0.0008352397,0.000006549447,0.00001264575,0.000133074,0.000008127826,0.000812131,0.9961733,0.00001452287,0.001331717,0.000005610411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865079,0.004087148,0.007984566,0.00006935847,0.00002644627,0.00005354422,0.0000666488,0.00006156287,0.001142792],"genre_scores_gemma":[0.9905121,0.001377128,0.00635933,0.00003300848,0.00001179899,0.00004405811,0.00007121188,0.0000125083,0.001578914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006115079,"threshold_uncertainty_score":0.002045691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02409038065089842,"score_gpt":0.3121189206869173,"score_spread":0.2880285400360189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}