{"id":"W2466897053","doi":"10.1021/ja710451s","title":"Site-Selective sp<sup>2</sup> and Benzylic sp<sup>3</sup> Palladium-Catalyzed Direct Arylation","year":2008,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":354,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Palladium; Selectivity; Diazine; Catalysis; Ligand (biochemistry); Yield (engineering); Combinatorial chemistry; Azine; Molecule; Stereochemistry; Medicinal chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005300668,0.0003550112,0.0007265295,0.00004723774,0.0003103346,0.00005229766,0.0004473281,0.00017659,0.0003574264],"category_scores_gemma":[0.0008591309,0.0002787063,0.0008111955,0.0007998753,0.0008212817,0.0002298701,0.0002169646,0.0008539289,0.00001188926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000610504,"about_ca_system_score_gemma":0.0002644105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001125277,"about_ca_topic_score_gemma":9.4763e-7,"domain_scores_codex":[0.997421,0.0001024322,0.0007841288,0.0004156171,0.0008583875,0.0004183885],"domain_scores_gemma":[0.9969321,0.0008710366,0.001089763,0.0004391497,0.0003817369,0.0002861927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000449272,0.0003603647,0.06058005,0.000102566,0.0009378318,0.00001562921,0.005720901,0.0072301,0.8843878,0.0000172886,0.03684975,0.003348473],"study_design_scores_gemma":[0.0051682,0.0001651554,0.02002889,0.0002642056,0.001009596,0.002353764,0.003247336,0.04895324,0.8863785,0.0009249121,0.02995142,0.00155473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962556,0.0002949642,0.0009180258,0.001053989,0.00004942708,0.00009662937,0.00004603255,0.00005414078,0.00123115],"genre_scores_gemma":[0.9900644,0.0003727582,0.006974823,0.000738556,0.001062267,0.0000076165,0.00004672278,0.0000636714,0.0006691509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04172314,"threshold_uncertainty_score":0.9999665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01498651648480636,"score_gpt":0.2585869954853492,"score_spread":0.2436004790005428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}