{"id":"W2467146152","doi":"10.1016/j.chom.2016.06.002","title":"CRIg Functions as a Macrophage Pattern Recognition Receptor to Directly Bind and Capture Blood-Borne Gram-Positive Bacteria","year":2016,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":231,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Lipoteichoic acid; Peptidoglycan; Biology; Microbiology; Staphylococcus aureus; Complement receptor; Bacteria; Macrophage; Complement system; Gram-negative bacteria; Complement receptor 1; Phagocytosis; Immunology; Antibody; In vitro; Escherichia coli; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001863779,0.000274113,0.000265302,0.000173531,0.0002726867,0.00004876834,0.0001307427,0.0003444767,0.003351605],"category_scores_gemma":[0.00006798566,0.0002117934,0.00008928787,0.0001498622,0.0001376497,0.0001934505,0.0001087601,0.0002053009,0.009930695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005442941,"about_ca_system_score_gemma":0.00005187909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002576376,"about_ca_topic_score_gemma":0.00003777814,"domain_scores_codex":[0.9984902,0.0002825735,0.0003139724,0.0004619825,0.00003008104,0.000421165],"domain_scores_gemma":[0.9992291,0.0001489301,0.0001291987,0.0002854898,0.0001485518,0.00005875495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003947005,0.0001095553,0.0001096733,0.00001836136,0.00009777473,0.000009990265,0.000775348,2.01626e-8,0.948567,0.000003820567,0.008694018,0.04121972],"study_design_scores_gemma":[0.001498824,0.0003483703,0.004810402,0.0001489809,0.0001038731,0.0001160521,0.0001606608,4.989566e-8,0.8933989,0.00001325366,0.09910131,0.0002993114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993542,0.001504949,0.0004062963,0.001288185,0.0009286128,0.0004784545,0.0004781908,0.00009181034,0.001281515],"genre_scores_gemma":[0.972378,0.0003822031,0.0001258885,0.0006262117,0.00008546372,0.00006369688,0.0007066295,0.00004369935,0.02558823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0904073,"threshold_uncertainty_score":0.9975595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005206324256600556,"score_gpt":0.1976011341715076,"score_spread":0.192394809914907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}