{"id":"W2467393554","doi":"10.3899/jrheum.160062","title":"Severe Rheumatoid Arthritis Developing in Conjunction with Gorlin Syndrome","year":2016,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Patched; Hedgehog signaling pathway; Vismodegib; Medicine; Smoothened; Hedgehog; Basal cell carcinoma; Cancer research; Nevoid basal-cell carcinoma syndrome; Basal Cell Nevus Syndrome; Progenitor cell; Genodermatosis; Pathology; Immunology; Stem cell; Biology; Cell biology; Signal transduction; Genetics; Gene; Basal cell","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001031345,0.00183264,0.001786358,0.001253355,0.001723856,0.001429089,0.001625705,0.01271788,0.003465175],"category_scores_gemma":[0.0077048,0.0007253198,0.001205344,0.0008192144,0.001345664,0.00170822,0.0007384272,0.0082538,0.001574363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001951651,"about_ca_system_score_gemma":0.0007001757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001432612,"about_ca_topic_score_gemma":0.002509752,"domain_scores_codex":[0.9987437,0.0003117265,0.000179951,0.000262238,0.0002376731,0.0002647691],"domain_scores_gemma":[0.9976134,0.001233216,0.0002614902,0.0001171644,0.0003271313,0.00044758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001376606,0.00005872291,0.003382788,0.0001440704,0.0000536821,0.9522266,0.0001994032,0.0001220967,0.0008459184,0.001167305,0.03685106,0.00481066],"study_design_scores_gemma":[0.0001464408,0.0001681991,0.005324378,0.0002734273,0.00009967768,0.9548329,0.0002383057,0.001184085,0.0005553737,0.001936393,0.03518359,0.00005712691],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1339989,0.0388311,0.004526682,0.6528968,0.1028325,0.000449341,0.0004842732,0.0007402459,0.06524025],"genre_scores_gemma":[0.5973266,0.01229144,0.002862831,0.1834953,0.1828044,0.000140893,0.0002150175,0.00014292,0.02072058],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01271788,"threshold_uncertainty_score":0.01416028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01085759835400767,"score_gpt":0.2185460480278818,"score_spread":0.2076884496738742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}