{"id":"W2467393554","doi":"10.3899/jrheum.160062","title":"Severe Rheumatoid Arthritis Developing in Conjunction with Gorlin Syndrome","year":2016,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Patched; Hedgehog signaling pathway; Vismodegib; Medicine; Smoothened; Hedgehog; Basal cell carcinoma; Cancer research; Nevoid basal-cell carcinoma syndrome; Basal Cell Nevus Syndrome; Progenitor cell; Genodermatosis; Pathology; Immunology; Stem cell; Biology; Cell biology; Signal transduction; Genetics; Gene; Basal cell","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007720673,0.0003492463,0.0008071673,0.0002082493,0.0001001121,0.00001549651,0.0004927338,0.0006562819,0.00002540708],"category_scores_gemma":[0.0001818924,0.0002028864,0.0001202173,0.0001178596,0.0002941828,0.000007541362,0.0001278114,0.000994482,0.00002030725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007541463,"about_ca_system_score_gemma":0.0004749629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004621602,"about_ca_topic_score_gemma":0.0001663955,"domain_scores_codex":[0.9977462,0.0004631198,0.0008146549,0.0002471774,0.0002626671,0.0004662293],"domain_scores_gemma":[0.9982273,0.0002080451,0.0009071945,0.0003470934,0.0002727762,0.00003756766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007149249,0.00002891124,0.03430208,0.0002955114,0.001438831,0.001147212,0.0004375951,0.00006755516,0.002410208,0.00004599777,0.9561329,0.002978252],"study_design_scores_gemma":[0.003765566,0.001182785,0.0009127374,0.004684862,0.00006552289,0.1843251,0.000245228,0.00000356915,0.001852414,0.0003797607,0.8016517,0.0009308074],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7782107,0.01054478,0.003520827,0.2062723,0.001023714,0.0002628552,0.00002195385,0.00001196833,0.0001309827],"genre_scores_gemma":[0.8616312,0.05517388,0.0009219347,0.08095738,0.0004140441,0.00002836034,0.00007064685,0.000189486,0.0006130792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1831778,"threshold_uncertainty_score":0.8273469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01085759835400767,"score_gpt":0.2185460480278818,"score_spread":0.2076884496738742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}