{"id":"W2467415850","doi":"10.1016/s1473-3099(16)30120-7","title":"Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 7-year follow-up of the phase 3, double-blind, randomised controlled VIVIANE study","year":2016,"lang":"en","type":"article","venue":"The Lancet Infectious Diseases","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":192,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of British Columbia; Université Laval; Dalhousie University; Nova Scotia Health Authority","funders":"GlaxoSmithKline","keywords":"Medicine; Cohort; Clinical endpoint; Vaccine efficacy; Vaccine trial; Internal medicine; Cohort study; Cervical cancer; HPV infection; Randomized controlled trial; Clinical trial; Vaccination; Immunology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003221314,0.001089383,0.002449031,0.0003355634,0.0003812437,0.0007736115,0.0008042096,0.002039617,0.002016474],"category_scores_gemma":[0.003094941,0.0006740931,0.001913433,0.0004253912,0.001162632,0.0009455236,0.0004420137,0.001839019,0.000367444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006333282,"about_ca_system_score_gemma":0.001020798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001850907,"about_ca_topic_score_gemma":0.001381164,"domain_scores_codex":[0.9987219,0.0007589716,0.0000682161,0.0001434294,0.0001182659,0.0001892555],"domain_scores_gemma":[0.9983285,0.0005588998,0.0004180142,0.0002067675,0.0001333163,0.0003545996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9725367,0.00653853,0.004516711,0.0002764349,0.001044269,0.00004021205,0.0001494839,0.0002253489,0.003465132,0.0000466403,0.0002658449,0.01089474],"study_design_scores_gemma":[0.6551628,0.3031907,0.03754658,0.00004077066,0.00154813,0.000057652,0.0001033408,0.0003086815,0.001081109,0.0001501939,0.000772999,0.00003722151],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974703,0.001402805,0.00009526035,0.00009011941,0.000057044,0.0003142004,0.0002693046,0.000009292058,0.0002917058],"genre_scores_gemma":[0.996767,0.0008980387,0.0002215735,0.0002020339,0.0001240574,0.0005011446,0.0004860163,0.000007600389,0.0007924153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003221314,"threshold_uncertainty_score":0.01703614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03125023980701402,"score_gpt":0.3448272627748398,"score_spread":0.3135770229678258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}