{"id":"W2467415850","doi":"10.1016/s1473-3099(16)30120-7","title":"Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 7-year follow-up of the phase 3, double-blind, randomised controlled VIVIANE study","year":2016,"lang":"en","type":"article","venue":"The Lancet Infectious Diseases","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":192,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of British Columbia; Université Laval; Dalhousie University; Nova Scotia Health Authority","funders":"GlaxoSmithKline","keywords":"Medicine; Cohort; Clinical endpoint; Vaccine efficacy; Vaccine trial; Internal medicine; Cohort study; Cervical cancer; HPV infection; Randomized controlled trial; Clinical trial; Vaccination; Immunology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009393854,0.000224905,0.001158599,0.0001001116,0.0001685902,0.00002264278,0.0004229743,0.00006729369,0.001182931],"category_scores_gemma":[0.000500638,0.00009249641,0.0003174816,0.0004796995,0.0002661853,0.0000567713,0.0002922812,0.0002658508,0.000004698352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001673994,"about_ca_system_score_gemma":0.0001465358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007187606,"about_ca_topic_score_gemma":0.0007762049,"domain_scores_codex":[0.9975787,0.0005698472,0.0005981775,0.0002839053,0.0005465521,0.0004227945],"domain_scores_gemma":[0.9977918,0.000694181,0.0002634992,0.0009468173,0.0001767557,0.0001269598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.582745,0.003708499,0.3922527,0.0001467016,0.001111052,0.000007806239,0.001540466,0.000003268267,0.006449308,0.0000917745,0.0002488415,0.01169453],"study_design_scores_gemma":[0.4830035,0.0005083032,0.5149837,0.00009470749,0.000274158,0.000002839034,0.0001759952,0.00000289825,0.0006178092,0.0001760757,0.00008322618,0.00007685142],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922033,0.0008810043,0.000004063952,0.0005328281,0.0001304391,0.004615407,0.00009266334,0.00004290889,0.001497362],"genre_scores_gemma":[0.9985909,0.0003749979,2.331668e-7,0.0001666818,0.0001937791,0.000265584,0.000004222262,0.00002842487,0.0003751565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1227309,"threshold_uncertainty_score":0.9997301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03125023980701402,"score_gpt":0.3448272627748398,"score_spread":0.3135770229678258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}