{"id":"W2467481365","doi":"10.2337/db15-1577","title":"Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling","year":2016,"lang":"en","type":"article","venue":"Diabetes","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Notch signaling pathway; Skeletal muscle; Endocrinology; Internal medicine; Biology; Myocyte; Myopathy; Signal transduction; Diabetes mellitus; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009555552,0.00008158229,0.00009189141,0.00001402854,0.00003431475,0.000005725373,0.00004553618,0.00006400597,0.00001584017],"category_scores_gemma":[0.00002665618,0.00004650433,0.00001512017,0.00004424369,0.0001328076,0.000004238706,0.0000267465,0.0000307837,0.000001734736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001447168,"about_ca_system_score_gemma":0.00001195852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009492001,"about_ca_topic_score_gemma":0.00001203226,"domain_scores_codex":[0.9995059,0.00004857122,0.00009344324,0.0001848526,0.00003421049,0.0001329714],"domain_scores_gemma":[0.999705,0.00006066311,0.00004766037,0.00012589,0.00003548658,0.00002529915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007296208,0.00001399248,0.2999326,0.00001893221,0.00001708034,2.975734e-8,0.00005376141,0.000001019282,0.6988357,0.000006002824,0.00006010401,0.0009877965],"study_design_scores_gemma":[0.0006958873,0.0002235,0.1963076,0.00003486665,0.00001980894,4.818352e-8,0.00006653422,0.00000691855,0.8016065,0.0003139529,0.0006318905,0.00009249163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982777,0.001264245,0.000007962472,0.00009680577,0.00002099827,0.00007595205,0.000008421915,0.000002858288,0.0002450554],"genre_scores_gemma":[0.9993092,0.0002284101,0.0000400372,0.0003170671,0.00002755615,0.000007166751,0.00001550615,0.000007902378,0.00004712053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.103625,"threshold_uncertainty_score":0.1896391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006354003236968479,"score_gpt":0.2071876179064845,"score_spread":0.200833614669516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}