{"id":"W2467570932","doi":"10.1089/aid.2015.0330","title":"Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection","year":2016,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"Fogarty International Center; National Institute of Allergy and Infectious Diseases; Harvard University; Harvard T.H. Chan School of Public Health; Canadian Institutes of Health Research; Harvard University Center for AIDS Research; National Institutes of Health; Center for AIDS Research, University of Washington; Michael Smith Health Research BC","keywords":"Epitope; Biology; Virology; Immune system; Human leukocyte antigen; Human immunodeficiency virus (HIV); Peptide sequence; Virus; Transmission (telecommunications); Chronic infection; Immunology; Antigen; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001962594,0.0001567534,0.0001903772,0.0003341865,0.0003527684,0.0004902881,0.0001257362,0.0001856701,0.00103139],"category_scores_gemma":[0.000999187,0.00008571402,0.0001396995,0.0002564166,0.0003355033,0.0002384669,0.0001826753,0.0002996552,0.0001276832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002931198,"about_ca_system_score_gemma":0.0001350251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001161911,"about_ca_topic_score_gemma":0.001722664,"domain_scores_codex":[0.9998785,0.00002382142,0.00001060263,0.00003567989,0.0000218676,0.00002954896],"domain_scores_gemma":[0.9994986,0.0001849783,0.0001774212,0.00003669705,0.00003526604,0.00006706271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004181686,0.00004171923,0.9447134,0.00002193508,0.0000467104,0.0007024994,0.0004660603,0.0004161593,0.04185104,0.0001398848,0.00006582217,0.01111671],"study_design_scores_gemma":[0.00001285919,0.0003591844,0.9836014,0.00001042391,0.00002932775,0.005307368,0.0004173623,0.001457554,0.008226415,0.0002169141,0.0003520927,0.000009148934],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997748,0.0000459434,0.00006277605,0.00000406402,4.677798e-7,8.197751e-7,0.0000197408,0.000001138815,0.00009030462],"genre_scores_gemma":[0.9997513,0.00002558666,0.0001223058,0.000005136777,0.000001786811,7.110129e-7,0.00004518435,0.000001411566,0.000046572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001161911,"threshold_uncertainty_score":0.003450394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05171563152605195,"score_gpt":0.314921947898629,"score_spread":0.263206316372577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}