{"id":"W2467575959","doi":"10.1099/jgv.0.000539","title":"Primary transmission of chronic wasting disease versus scrapie prions from small ruminants to transgenic mice expressing ovine or cervid prion protein","year":2016,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"Agricultural Research Service; U.S. Department of Agriculture","keywords":"Chronic wasting disease; Scrapie; Biology; Virology; Transmission (telecommunications); Inoculation; Transmissible spongiform encephalopathy; Clinical disease; Disease; Prion protein; Immunology; Pathology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002488415,0.0002112793,0.0003358687,0.0001066479,0.00009281026,0.000012732,0.0003594057,0.0001643851,0.0001527276],"category_scores_gemma":[0.0001488379,0.0001403483,0.000251254,0.00008786004,0.00007472865,0.00001789707,0.00009834868,0.0001204395,0.000002100417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006583767,"about_ca_system_score_gemma":0.0004948733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008558352,"about_ca_topic_score_gemma":0.00001687814,"domain_scores_codex":[0.9983605,0.0001898418,0.0006038586,0.0003144474,0.000192027,0.0003393854],"domain_scores_gemma":[0.9988138,0.00004746153,0.0003957282,0.0002597047,0.0001146492,0.0003686748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007586903,0.0001245588,0.0003915616,0.00009233724,0.00008636681,0.00001576758,0.00002968846,0.000149285,0.85798,0.000003213234,0.0001287601,0.1334115],"study_design_scores_gemma":[0.006456084,0.003448414,0.01976095,0.001218553,0.000211519,0.00002276149,0.00001182316,0.00008667383,0.9457636,0.000081381,0.0225684,0.0003698716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9579288,0.01874724,0.02154975,0.001126961,0.0002975366,0.0002853193,0.00004739415,0.000005891377,0.00001113145],"genre_scores_gemma":[0.9857474,0.003895476,0.008879826,0.0001727944,0.001069908,0.00001536002,0.00001987969,0.00003694152,0.0001624342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1330417,"threshold_uncertainty_score":0.5723239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02036333046226921,"score_gpt":0.2624144298183385,"score_spread":0.2420510993560692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}