{"id":"W2467575959","doi":"10.1099/jgv.0.000539","title":"Primary transmission of chronic wasting disease versus scrapie prions from small ruminants to transgenic mice expressing ovine or cervid prion protein","year":2016,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"Agricultural Research Service; U.S. Department of Agriculture","keywords":"Chronic wasting disease; Scrapie; Biology; Virology; Transmission (telecommunications); Inoculation; Transmissible spongiform encephalopathy; Clinical disease; Disease; Prion protein; Immunology; Pathology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003010491,0.0006873862,0.0003209784,0.0005631134,0.0001694885,0.0003524487,0.0002327636,0.000412794,0.001047113],"category_scores_gemma":[0.0001452797,0.0002372343,0.0003198732,0.0001883927,0.0003780188,0.0002956007,0.0002141685,0.000972879,0.0003144179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003082616,"about_ca_system_score_gemma":0.0001653752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006409275,"about_ca_topic_score_gemma":0.0009540352,"domain_scores_codex":[0.9997048,0.00004364263,0.00003515463,0.0001126318,0.00003958309,0.00006423371],"domain_scores_gemma":[0.9996265,0.00006494515,0.0001170151,0.00004208775,0.00003594895,0.0001134636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003378034,0.00009524584,0.0006474957,0.00002806843,0.000007883958,0.00005990707,0.00003755125,0.00001612255,0.9983194,0.00003781481,0.00001822859,0.0003945881],"study_design_scores_gemma":[0.00006538791,0.004728944,0.02891775,0.00003053112,0.00008346899,0.001195082,0.0001215641,0.000954665,0.9627723,0.0000887548,0.001031094,0.00001039527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978957,0.0004122334,0.000795179,0.00002653041,0.00001066891,0.00004087707,0.0003051863,0.00003384681,0.0004796511],"genre_scores_gemma":[0.9938059,0.0007829142,0.001924347,0.00006581314,0.00001243733,0.0001065791,0.0008900999,0.00002310419,0.00238889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001047113,"threshold_uncertainty_score":0.003502905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02036333046226921,"score_gpt":0.2624144298183385,"score_spread":0.2420510993560692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}