{"id":"W2467579863","doi":"10.1016/j.devcel.2016.05.015","title":"A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing","year":2016,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":116,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institutes of Health; Novo Nordisk Fonden; Danmarks Frie Forskningsfond; Villum Fonden; National Institute of General Medical Sciences; Novo Nordisk; Natur og Univers, Det Frie Forskningsråd","keywords":"Biology; Drosophila (subgenus); Steroid hormone; Drosophila melanogaster; Hormone; Genome; Genetics; Cell biology; Computational biology; Evolutionary biology; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001740994,0.0007118477,0.0004349776,0.00072611,0.000338322,0.0005199725,0.0003226496,0.0002956308,0.00203337],"category_scores_gemma":[0.0001564995,0.0002969826,0.0003685759,0.000541764,0.0002431849,0.0001531587,0.0003347215,0.0003696481,0.0003923616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005035822,"about_ca_system_score_gemma":0.0004181339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003878113,"about_ca_topic_score_gemma":0.02030966,"domain_scores_codex":[0.9998385,0.00001103067,0.000009197243,0.00006489948,0.00005018391,0.00002625431],"domain_scores_gemma":[0.9998754,0.00003219377,0.00004341609,0.000009594193,0.00001206066,0.00002740293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002119731,0.00001696404,0.003649964,0.0000579332,0.00005528879,0.0001624205,0.00001288219,0.0001104916,0.9917923,0.00008416669,0.0003896206,0.003455983],"study_design_scores_gemma":[0.0001519394,0.0003910211,0.2481257,0.00002407158,0.0006077919,0.00109944,0.0001476608,0.002303278,0.7351798,0.0001442578,0.01178235,0.00004259688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754591,0.005198004,0.003472155,0.0002506044,0.00006341594,0.00006789692,0.01108237,0.0004488921,0.003957655],"genre_scores_gemma":[0.9810931,0.002218254,0.003828741,0.0004014149,0.00001774917,0.0000487301,0.007516585,0.000108513,0.004766898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003878113,"threshold_uncertainty_score":0.007711112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03169051731163346,"score_gpt":0.2451782457803957,"score_spread":0.2134877284687622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}