{"id":"W2467579863","doi":"10.1016/j.devcel.2016.05.015","title":"A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing","year":2016,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":116,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institutes of Health; Novo Nordisk Fonden; Danmarks Frie Forskningsfond; Villum Fonden; National Institute of General Medical Sciences; Novo Nordisk; Natur og Univers, Det Frie Forskningsråd","keywords":"Biology; Drosophila (subgenus); Steroid hormone; Drosophila melanogaster; Hormone; Genome; Genetics; Cell biology; Computational biology; Evolutionary biology; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002177018,0.0001818532,0.0002074644,0.000171644,0.0002478274,0.00001618158,0.0002322499,0.00008515783,0.00008113022],"category_scores_gemma":[0.0002670644,0.0001359958,0.00003264412,0.000209329,0.000591221,0.0003089115,0.0003279962,0.0001211184,0.000136097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007198309,"about_ca_system_score_gemma":0.00009206121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004462611,"about_ca_topic_score_gemma":0.000003830721,"domain_scores_codex":[0.9984373,0.0001279258,0.0003201154,0.0005718604,0.0001932437,0.0003495564],"domain_scores_gemma":[0.9994628,0.0001818564,0.0001081633,0.0001288015,0.00003459935,0.00008382411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001216837,0.00005465495,0.008746603,0.00002084854,0.000007643684,0.000009421999,0.0003606401,2.185233e-7,0.9897549,0.00002039588,0.0004320131,0.0004709481],"study_design_scores_gemma":[0.0003292271,0.00008529096,0.1398832,0.00002389721,0.000003196177,0.0000703004,0.00009562502,5.00952e-7,0.8587712,0.0002078005,0.0003684186,0.0001613943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975756,0.00006205363,0.0000114539,0.0002273198,0.0001288994,0.0002797508,0.00001567936,0.00004223281,0.001657005],"genre_scores_gemma":[0.9954365,0.0001422067,0.0004199937,0.0001546128,0.00002895172,0.0000196684,0.000005919874,0.00001969623,0.003772483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1311366,"threshold_uncertainty_score":0.5545747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03169051731163346,"score_gpt":0.2451782457803957,"score_spread":0.2134877284687622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}