{"id":"W2468048255","doi":"10.1002/dta.2011","title":"Mass spectrometric characterization of the hypoxia‐inducible factor (HIF) stabilizer drug candidate BAY 85‐3934 (molidustat) and its glucuronidated metabolite BAY‐348, and their implementation into routine doping controls","year":2016,"lang":"en","type":"article","venue":"Drug Testing and Analysis","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Analyte; Urine; Metabolite; Drug; Solid phase extraction; Chemistry; Chromatography; Pharmacology; Mass spectrometry; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004004577,0.000232442,0.0004169327,0.0002432073,0.0001982204,0.00006890733,0.0001136455,0.00006051481,0.00001944463],"category_scores_gemma":[0.0003005454,0.0001435929,0.00009945615,0.0009155842,0.00009093366,0.00003171259,0.0001177571,0.00006953927,2.49097e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001837339,"about_ca_system_score_gemma":0.00006391274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003028102,"about_ca_topic_score_gemma":0.0002234727,"domain_scores_codex":[0.9985383,0.0001699057,0.0003851732,0.0004827729,0.0001418423,0.0002819725],"domain_scores_gemma":[0.9989877,0.00009892678,0.0003450084,0.00027538,0.0001854447,0.0001075222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002172516,0.00001415937,0.0772393,0.00002700503,0.0003335644,1.278572e-7,0.0002815108,0.00000422507,0.9099396,0.00002216877,0.000004633714,0.01211192],"study_design_scores_gemma":[0.001803558,0.0000479144,0.2789192,0.00003709673,0.0008460798,0.000004460758,0.0003249877,0.0009021857,0.7152101,0.0001158899,0.001458617,0.0003298739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944124,0.003352715,0.001153513,0.0003447736,0.00009510511,0.0002407518,0.0003691099,0.00001527918,0.00001630762],"genre_scores_gemma":[0.9975117,0.001636511,0.0001943249,0.00006952618,0.0001984365,0.00001710543,0.0001458682,0.00001946149,0.0002070635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2016799,"threshold_uncertainty_score":0.5855549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048983081347024,"score_gpt":0.2460509351613392,"score_spread":0.235561104347869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}