{"id":"W2468311487","doi":"10.1016/s1470-2045(16)30120-6","title":"Toxicity and quality of life after adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): an open-label, multicentre, randomised, phase 3 trial","year":2016,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":177,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Université de Sherbrooke","funders":"Canadian Cancer Society Research Institute; KWF Kankerbestrijding; Agenzia Italiana del Farmaco, Ministero della Salute; National Health and Medical Research Council; Cancer Research UK","keywords":"Medicine; Endometrial cancer; Chemoradiotherapy; Adjuvant; Oncology; Radiation therapy; Quality of life (healthcare); Open label; Internal medicine; Cancer; Clinical trial; Gynecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001925949,0.0002968928,0.002416503,0.0001030309,0.00009686677,0.00002322846,0.0003252667,0.0001758446,0.0006715321],"category_scores_gemma":[0.0007581806,0.0001396333,0.00006922795,0.0003103276,0.0003550297,0.0001444517,0.00005215282,0.0001614508,0.000001323563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005409273,"about_ca_system_score_gemma":0.000437003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001173198,"about_ca_topic_score_gemma":0.0008373658,"domain_scores_codex":[0.997324,0.0006431877,0.0006720482,0.00049721,0.0003105333,0.0005529627],"domain_scores_gemma":[0.9955624,0.002762988,0.0006124379,0.0005583771,0.0001518531,0.000351945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8459814,0.003285695,0.001465581,0.00006198631,0.00135416,0.000007686333,0.0004146291,5.591205e-7,0.01070276,0.00003988947,0.0001116162,0.1365741],"study_design_scores_gemma":[0.9411598,0.04468994,0.003245842,0.00003535757,0.0003689753,0.000003173663,0.00007083798,0.00001244314,0.003352907,0.0000935358,0.006762132,0.0002050532],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882762,0.002079047,0.0003994168,0.002732185,0.0007580493,0.005007878,0.000619348,0.00003854521,0.00008934447],"genre_scores_gemma":[0.984654,0.006214741,0.002385806,0.001256199,0.002637731,0.002583261,0.00001618327,0.00004657138,0.000205475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.136369,"threshold_uncertainty_score":0.7352806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1089215856213066,"score_gpt":0.4203140416483053,"score_spread":0.3113924560269987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}